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Previous Announcements

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Sponsored by the Brigham Research Institute: Cores and Resources Fair on Monday, June 19, at 12 PM in the BTM Café Atrium!

Posted on June 18, 2017

Dear Core Users, Members of the Partners Research Community,

We are looking forward to chat with you about our diverse portfolio of service capabilities at our table during the Core Fair. Please stop by!

Core Fair 12-2 PM

Monday, June 19, 2017

BTM Café Atrium (60 Fenwood Rd, 1st floor, Boston)


Directions: Enter at 60 Fenwood Rd main entrance. Take the lobby staircase to the 1st floor. The BTM Café Atrium (open space) is across from the BTM Café.

See you then!

~ The MGH CCIB DNA Core Team

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MGH CCIB DNA Core Facility Closed for Memorial Day
(May 29, 2017)

Posted on May 22, 2017

Dear Core Users,
In observance of Memorial Day, the DNA Core Facility will be closed on Monday, May 29, 2017. Our Courier service will not be operating on this day, and samples will not be picked up from or delivered to our remote drop box locations. Our on-site drop box will be only accessible with a key card as the entrance to the Clark Building (38 Sidney Street, Cambridge, MA) will be locked.

If you should need any help planning your orders with us, please don't hesitate to contact us.

We hope you'll enjoy the Memorial Day Weekend!

Sincerely,

The MGH CCIB DNA Core Staff

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Important Update: Winter Storm Closing

Posted on March 14, 2017

The MGH CCIB DNA Core facility is closed today to ensure the safety of our staff. Some delays in sample processing and data delivery should be expected. Samples will not be picked up from our remote dropboxes today.

We are planning to reopen tomorrow, Wednesday, March 15, 2017.

Stay safe !

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Our 1st Sample Dropbox in the Longwood Medical Area!

Posted on February 17, 2017

We are pleased to announce that we now have a sample dropbox in the new Brigham and Women's Building for Transformative Medicine at 60 Fenwood Road.

Our new dropbox is located on the building's ground floor, in the room next to the freight elevators (also accessible directly from the loading dock on Vining Street).

Samples will be picked up every Wednesday at 3:00 PM.

Courier service for this new dropbox will officially start on Wednesday, February 22, 2017. Please place your samples and a copy of your order form in the dropbox BEFORE 3:00 PM.

Sincerely,

The MGH CCIB DNA Core Team

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MGH CCIB DNA Core Facility Closed for Presidents' Day (February 20, 2017)

Posted on February 15, 2017

Dear Core Users,

In observance of Presidents' Day, the DNA Core Facility will be closed on Monday, February 20, 2017. Our Courier service will not be operating on this day, and samples will not be picked up from or delivered to our remote drop box locations.
Our on-site drop box at 38 Sidney Street (Cambridge, MA) will be accessible on this day. Please note that samples will be kept at ambient temperature until Tuesday morning, February 21.

If you should need any help planning your orders with us, please don't hesitate to contact us.

Sincerely,

The Core Staff

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Winter Storm Closing

Posted on February 9, 2017

Due to the inclement weather, our core facility is closed today for the safety of our staff. Orders will not be processed, and samples will not be picked up from our remote dropboxes today.

We will resume our normal business hours tomorrow, Friday, February 10, at 8 am.

Stay safe and warm.

- The MGH CCIB DNA Core Team

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Holiday Closure Announcement

Posted on December 14, 2016

Dear Core Users,

Our facility will be closed on Monday, December 26 and on Monday, January 2, 2017 due to Christmas and New Year's holidays. On both days, our courier service will not be operating, and our on-site dropbox will be only accessible with a key card as the entrance to the building will be locked.

The entire CCIB DNA Core team wishes you a safe and happy holiday season. We would also like to take this opportunity to thank you for your business this year. It has been a pleasure helping you reach your goals, and we look forward to contributing to your success in 2017.

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USER ALERT!

Scheduled Server Maintenance: Permanent Deletion of Old Data Files on Sunday, January 1, 2017

Posted on November 28, 2016

Dear Users,

On Sunday, January 1, 2017, we will permanently remove all old sequencing data files from our server. We strongly encourage you to download all of your data that were generated at our core facility before January 1, 2016.

Please accept our apologies for the inconvenience.

~ The CCIB DNA Core Team

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Effective October 1, 2016: FY17 Service Fees

Posted on September 19, 2016

Dear Core Users:

Our FY'17 service fee structure has now been set after discussion with Partners Research Finance Management and goes into effect as of October 1, 2016. The new service fees reflect small increases in the costs of reagents, consumables and labor, and these fees support both our continuous process improvement efforts and the implementation of additional and/or improved service features, in particular for our high-demand Next-Gen Sequencing applications. Although we would like to keep our current rates, these increases were mandated by Partners policies that dictate that Cores recover their operating costs while not generating revenues in excess of their operating costs. Please be assured that we have done our best to hold down costs for you but we do not want to compromise on quality. Our new rates guarantee that we can continue to provide the same level of quality and service that you have come to expect from us.

All orders that started being processed this month but are completed on or after October 1, 2016, will be invoiced at current (FY'16) pricing. Orders that are placed close to the end of September but are not processed before October 1, 2016, will be invoiced according to our new FY'17 pricing structure.

We appreciate your past patronage and look forward to serving your future research needs.

~ The CCIB DNA Core Team

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Thanksgiving Holiday Schedule

Posted on November 17, 2016

Dear Core Users,

The CCIB DNA Core will be closed November 24 and November 25, 2016. Our Courier Service is not operating on either day, and samples will not be picked up from any of our remote dropbox locations. Direct sample drop-off at 38 Sidney Street is also not available on both days since the entrance to the main building (The Clark Building) will be locked on both days. The core facility will resume its regular business hours on November 28, 2016.

Please note that you might experience 2 to 3 business days of delay in the processing of your order(s) due to the holiday break. We are working very hard to reduce this delay as much as possible - but we simply believe that our dedicated core team deserves the opportunity to spend Thanksgiving with their families. If you have specific questions about your order or are concerned about the availability of your data, please contact us at dnacore@ccib.mgh.harvard.edu.

Thank you for being our valued customers. We are grateful for the pleasure of serving you and meeting your research needs.

We wish you a lovely Thanksgiving and a joyous holiday season.

Nicole Stange-Thomann, Ph.D.
Director, CCIB DNA Core

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CCIB DNA Core Facility Closed for Columbus Day
(October 10, 2016)

Posted on October 5, 2016

Dear Core Users,

In observance of Columbus Day, the DNA Core Facility will be closed on Monday, October 10, 2016. Our Courier service will not be operating on this day, and samples will not be picked up from or delivered to our remote dropbox locations. Our on-site dropbox will be accessible on this day. Please note that samples will be kept at ambient temperature until Tuesday morning, October 11.

If you should need any help planning your orders with us, please don't hesitate to contact us.

Happy Columbus Day!

Sincerely,

The CCIB DNA Core Staff

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CCIB DNA Core Facility Closed for Labor Day
(September 5, 2016)

Posted on August 30, 2016

Dear Core Users,

In observance of Labor Day, the DNA Core Facility will be closed on Monday, September 5, 2016. Please note that our courier service will not be operating on this day; samples will not be picked up from our remote dropbox locations, and orders will not be delivered to any dropbox.
Our on-site drop box will be only accessible with a key card as the entrance to the Clark Building (38 Sidney Street, Cambridge, MA) will be locked on this day.

If you should need any assistance planning your orders with us, please don't hesitate to contact us.

Wishing you a Happy Labor Day!

The CCIB DNA Core Staff

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Holiday Closure on Monday, July 4, 2016: Observance of Independence Day

Posted on June 27, 2016

The CCIB DNA Core Facility will be closed on Monday, July 4, 2016 in observance of Independence Day.

Our Courier service will not be operating on this day, and samples will not be picked up from or delivered to our remote dropbox locations. Our onsite dropbox will be only accessible with a key card as the entrance to the Clark Building (Suite 100, 38 Sidney Street, Cambridge, MA) will be locked.

Service turnaround times may be slightly longer as we expect larger order volumes due to the holiday. We are doing our best to process your orders as quickly as possible.

If you should need any help planning your orders with us, please don't hesitate to contact us.

Wishing you a happy, safe 4th of July!

~ The Core Team

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CCIB DNA Core Facility Closed for Memorial Day
(May 30, 2016)

Posted on May 23, 2016

Dear Core Users,

In observance of Memorial Day, the DNA Core Facility will be closed on Monday, May 30, 2016. Our Courier service will not be operating on this day, and samples will not be picked up from or delivered to our remote drop box locations. Our on-site drop box will be only accessible with a key card as the entrance to the Clark Building (38 Sidney Street, Cambridge, MA) will be locked.

If you should need any help planning your orders with us, please don't hesitate to contact us.

We hope you'll enjoy the Memorial Day Weekend!

Sincerely,

The CCIB DNA Core Team

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Contact Us   We want to hear from you!

   Posted on May 13, 2016


We need your feedback to assess the demand for a sample dropbox in the Longwood Medical and Academic area.

If your lab is in the Longwood area, please take a few minutes out of your busy schedule and tell us, which of our services you are using (or are planning to use in the near future), and on how many days per week you would need our sample pick-up service.

Thank you!

~ The CCIB DNA Core Team

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Meet Us

BWH Research Cores Fair: Monday, April 25, 2016, 12-2 PM

Meet us and learn more about our core and our research services!
We are looking forward to seeing you at our table from 12-2 PM in Carrie Hall!

Posted on April 20, 2016

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Updated: List of Core-contributed PublicationsThanks

Posted on March 3, 2016

We'd like to express our gratitude to all of our users who are formally acknowledging the contributions of the CCIB DNA Core in their publications!

Please check out our updated publication list here.

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Winter Storm Causes Slight Turnaround Time Delay

Posted on February 8, 2016

Due to inclement weather, a slight delay in processing your order can be expected. Your patience is greatly appreciated.

Turnaround times will go back to normal core operations tomorrow, Tuesday, February 9, 2016.

Sincerely,
The CCIB DNA Core Team

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USER ALERT!


Scheduled Server Maintenance: Permanent Deletion of Old Data Files on Monday, February 1, 2016

Posted: January 8, 2016

Dear Users,

On Monday, February 1, 2016, we will permanently remove all old sequencing data files from our server. We strongly encourage you to download all of your data that were generated at our core facility before January 1, 2015.

Please accept our apologies for the inconvenience.

~ The CCIB DNA Core Team

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Connect With Us on Facebook and Twitter

Posted on December 23, 2015

Like us. Follow us. Tweet us. Join us.

There's a whole lot more to learn about us. You now have a new way online to connect with the CCIB DNA Core and stay abreast of our latest news. Simply click on the social media buttons at the top of our webpage (right below our webpage banner), and you will be automatically directed to our new networking sites.

On our Facebook page, you'll find postings about our services, special events and updates, important announcements, lots of pictures and short videos of our lab processes and our various automated platforms in action, and much more. Plus, you can follow our news, announcements, and service updates and highlights via Twitter.

So, Like us and Follow us today!

New Sample Dropbox at the Ragon Institute!NEW

Posted on November 9, 2015

We are pleased to announce the establishment of a new sample dropbox location in the lobby (1st floor) of the Ragon Institute of MGH, MIT and Harvard. Free pickup service will be provided Mondays through Fridays (with the exception of official MGH Holidays).

Courier service for this new dropbox will officially start on Wednesday, November 11, 2015. Please place your samples and a copy of your order form in the dropbox no later than 11 AM.

Sincerely,
The CCIB DNA Core Team

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Effective October 1, 2015: FY16 Service Fees

Posted on September 23, 2015

Dear Core Users:

Our FY16 service fee structure has now been set after discussion with Partners Research Finance Management and will be effective October 1, 2015. The new service fees reflect the continuing increases in the costs of reagents, consumables and labor, and allow us to guarantee that the top-quality of our services will not be compromised in any way and to sustain our continued process improvements efforts. Although we would very much like to retain our current rates, these increases were mandated by Partners policies that dictate that Cores recover their operating costs while not generating revenues in excess of their operating costs.

Thank you for your continuing patronage and support!

~ The CCIB DNA Core Team

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USER ALERT!

Scheduled Server Maintenance: Permanent Deletion of Old Data Files on Wednesday, April 15, 2015

Posted on March 25, 2015

Dear Users,

On Wednesday, April 15, 2015, we will permanently remove all old sequencing data files from our server. We strongly encourage you to download all of your data that were generated at our core facility before January 1, 2014.

Please accept our apologies for the inconvenience.

~ The CCIB DNA Core Team

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NEW SERVICE ANNOUNCEMENT!

CCIB DNA Core Introduces 2nd NGS-based Application: CRISPR SEQUENCING

Posted on February 25, 2015

We are pleased to announce the official launch of our new service - CRISPR Sequencing - a cost-effective, high-throughput strategy for identifying CRISPR/Cas-induced mutations using next-generation sequencing technology.

Our new service is offered on a weekly basis, with its first official run taking off on Wednesday, March 4, 2015. If you would like to submit samples and haven't been part of our beta-testing phase, please
contact us so we can activate your account.

Please explore our website to learn more!

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NEW on our Website: Convenient "ORDER NOW" Feature!

Posted on February 9, 2015

To make the order process easier and more efficient for our customers, we added a new ORDER NOW feature to our website. From now on you will see a new button called "ORDER NOW" which will be displayed on the top of our webpage. When you successfully logged into your account, just click this button and you will have the convenience of simply choosing the desired service from the menu. You will immediately be taken to the corresponding order form.

We hope that you find this to be a convenient feature and look forward to your feedback.

Enjoy.


- The CCIB DNA Core Team

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Service Schedule Change

Complete Plasmid Sequencing - Now Offered Every Week

Posted: January 7, 2015


Due to the continuously increasing demand for our new and unique service, we are now offering a new service cycle every week. Turnaround time will be 8 to 9 business days (calculated from the submission deadline) but might vary slightly dependent on order volumes.

For additional service details and important updates and announcements, please visit the respective service page here.

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CCIB DNA Core Facility closed for Martin Luther King's Day (January 19, 2015)

Posted on January 15, 2015

Dear Core Customers:

In observance of Martin Luther King's Birthday, the CCIB DNA Core Facility will be closed on Monday, January 19, 2015. Our Courier service will not be operating on this day, i.e. samples will not be picked up from or delivered to our remote dropbox locations. Our on-site dropbox at 38 Sidney Street (Cambridge, MA) will be accessible on this day. Please note that samples will be kept at R.T. until Tuesday morning, January 20.

Please be advised to plan your experiments according to the relevant deadlines:

  • Sanger Sequencing / Fragment Analysis (Microsatellite/MLPA)

    Friday, 01-16-2015 - Samples received by 12:00 PM will be entering the production pipeline on the same day, and data will be posted on Tuesday, January 20, 2015.

  • Complete Plasmid Sequencing

    Data for samples submitted by January 7, 2015 should be available as early as Tuesday, January 20. Processing time for samples submitted in time for the January 14 deadline is not expected to increase.

  • DNA Synthesis

    Friday, 01-16-2015 - All oligonucleotide orders received before 5 PM will be outsourced to IDT. Dependent on IDT's shipping schedule, oligos will be delivered to our remote dropboxes on Tuesday, January 20 or on Wednesday, January 21.

  • Laboratory Automation

    Plasmid DNA Preparation: All orders received on Friday, January 16, 2015 will be processed on Tuesday, January 20.

    Mouse Genotyping: To ensure the standard weekly turnaround, orders have to be submitted and samples have to be received at the core laboratory no later than 1:00 PM on Tuesday, January 20. Results for all orders received on January 20 will be available on Friday, January 23.

If you should need any help planning your orders with us, please don't hesitate to contact us.

Sincerely,

The CCIB DNA Core Staff

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CCIB DNA Core Holiday Schedule

Posted: December 23, 2014

The CCIB DNA Core will be following a modified holiday schedule in observance of Christmas Day (December 25, 2014) and New Year's Day (January 1, 2015). Our normal schedule will resume on Friday, 01-02-2014. Please see below for details.

  • Sanger Sequencing / Fragment Analysis (Microsatellite/MLPA)

    Wednesday, 12-24-2014 - Samples received by 12:00 PM will enter the production pipeline on the same day, and data will be posted on Friday, December 26, 2014.

    Wednesday, 12-31-2014 - Samples received by 12:00 PM will be processed on the same day, and data will be posted on Friday, December 26, 2014.

  • Complete Plasmid Sequencing

    All samples submitted in time for the December 17 deadline are currently being processed. The corresponding NGS run followed by automated sequence assembly will be slightly delayed due to reduced staffing. As soon as the data becomes available, we will send out email notifications.

  • DNA Synthesis

    Wednesday, 12-24-2014 through Friday, 12-26-2014 - All oligonucleotide orders will be outsourced to IDT. Dependent on IDT's shipping schedule, oligos will be delivered to our remote dropboxes on Monday, December 29 or on Tuesday, December 30.

    Monday, 12-29-2014 - Our normal in-house DNA Synthesis will resume.

  • Mouse Genotyping

    Monday, 12-22-2014 - Results for all Mouse Genotyping orders received this Monday will be available on Wednesday, 12-24-2014.

    Monday, 12-29-2014 - Results for all Mouse Genotyping orders received on this day (before 1:00 PM) will be available on Wednesday, 12-31-2014.

  • 96-well Plasmid DNA Preparation

    Wednesday, 12-24-2014 - Dependent on the total number of service requests, orders might not be processed before Friday, 12-26-2014.

    Wednesday, 12-31-2014 - Dependent on the total number of service requests, orders might not be processed before Friday, 01-02-2014.

We thank you for your loyalty and patronage throughout this year, and we look forward to continue supporting your research needs in 2015.

Wishing you a wonderful Holiday Season and a happy, healthy, and successful New Year!

The CCIB DNA Core

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MGH Research Core Day

Monday, December 22, 2014
1:00 - 3:00 PM

Simches 3rd Floor Conference Area

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Dear Customers,

Please stop by our table to learn what the CCIB DNA
Core has to offer and speak with us about
our brand-new services.

Light refreshments will be provided, along with a raffle!

We hope to see you all on Monday, December 22, 2014!

~ The CCIB DNA Core Team ~

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NEW SERVICE ANNOUNCEMENT

Complete Plasmid Sequencing - a unique NGS application

Posted: September 4, 2014

The CCIB DNA Core is excited to announce the official launch of its first and unique NGS-based service application.

Our new Complete Plasmid Sequencing service combines massively parallel sequencing with automated sequence assembly and offers many advantages over conventional Primer Walking services, including high sequencing coverage, attractive pricing and faster turnaround.

For additional service details and important updates and announcements, please visit the respective service page here.

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CCIB DNA Core Facility closed for Labor Day (September 1, 2014)

Posted: August 27, 2014

Dear Core Customers,

In observance of Labor Day, the DNA Core Facility will be closed on Monday, September 1, 2014. Our Courier service will not be operating on this day, i.e. samples will not be picked up from or delivered to our remote drop-box locations. Our on-site drop-box will also not be accessible as the entrance to the building will be locked.

Please be advised to plan your experiments/orders according to the relevant deadlines:

  • Sequencing data for samples submitted in time for courier pick-up on Friday, August 29, will be available on Tuesday, September 2.

  • Oligonucleotide synthesis orders received on Friday, August 29 (before 5 pm!) will be delivered and/or available for pick-up on Tuesday, September 2. All orders placed between August 30 and September 1 will be ready on Wednesday, September 3.

  • 96-well Plasmid DNA Preparation orders received on Friday, August 29, will be processed on the same day or - dependent on the respective order volumes - on Tuesday, September 2. These orders will be entering the DNA sequencing pipeline and/or will be delivered to the corresponding drop-box location(s) on Tuesday, September 2 or on Wednesday, September 3.

  • To ensure the standard weekly turnaround of our Mouse Genotyping services, orders should be submitted by Tuesday, September 2 and must be received by our core facility before 1 pm. Results for all orders received on September 2 will be available on Friday, September 5.

If you should need any help planning your orders with us, please don't hesitate to contact us.

Happy Labor Day!

The CCIB DNA Core Staff

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WELCOME to our NEW WEBSITE !

Posted: July 8, 2014

The CCIB DNA Core is excited to announce the launch of its newly designed and improved website, which goes live today, Tuesday 8th July 2014 and is located at this URL address: https://ccibtest0.mgh.harvard.edu:8443/new-cgi-bin/.

Our goal for the new website is to improve user friendliness, usability and appeal and to provide our current and prospective customers with an easier way to learn about our service portfolio with most accurate information. The new segmentation of the entrance to our service portfolio allows visitors to enter either via the service category or via a specific service of interest. Our clients can access information easily and on their own choice rather than sift through everything to decide and/or to find what is of interest to them. The addition of a search functionality to the new site allows to search the website content. The website will be updated on a regular basis, with news, service launches and new content.

For the next couple of weeks, you will be able to toggle between the new and the old site. Once the old site retires, you will be automatically redirected to the new URL.

If you should experience any problems viewing the new website with your PC or MAC or notice that any links are not working, please do get in touch to let us know.

If you have any questions, comments or suggestions, please contact us via email or leave us your thoughts in our feedback form. We would really welcome your comments both positive and negative.

We hope you will enjoy our new site, finding more service options and information each time!

The CCIB DNA Core Team

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On-site Oligonucleotide Pick-Up Station Moves to 65 Landsdowne Street

Posted: May 9, 2014

Dear Users of our DNA Synthesis Services,

As of Monday, May 12, 2014, our current onsite pick-up station (38 Sidney Street, Cambridge, MA) will be moved to the Partners Research Building (65 Landsdowne Street, Cambridge, MA). This new pick-up station will be located behind the security desk in the lobby (1st floor) to provide convenient and easy access to your oligonucleotide orders.

As usual, orders will be available for personal pick-up at this new location around 4 pm. Our onsite pick-up location will be discontinued.

Sincerely,
The CCIB DNA Core Team

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Partners in Excellence Award for a CCIB DNA Core Staff Professional!

Posted on March 21, 2014

We are proud to announce that John Darga, Manager of our Laboratory Automation group, was nominated for and selected to receive an Individual 2013 Partners in Excellence award in the area of teamwork.

John will be recognized at the MGH award celebration on Thursday, April 24, 2014, at 2.00 pm in the Bullfinch patio tents.

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Now Available: Additional Sequencing Sample Dropbox in Lobby of Simches Building!

Posted on January 14, 2014


Dear CCIB DNA Core Users,

We are pleased to announce that we have established an additional dropbox location for your sequencing samples. The new dropbox is conveniently located in the lobby (1st floor) of the Simches Building, in front of the glass wall on the left side of the entrance. Also for this new dropbox location, free pickup service is available Mondays through Fridays (with the exception of official MGH Holidays). Samples will be picked up at 10 am and delivered to our Core Facility in time for the day's queue. Please place your samples and a copy of your order form in the dropbox before the cut-off time.

Please note that we will also continue to service our original dropbox on the 7th floor of the Simches Building.

Sincerely,
The CCIB DNA Core Team

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Effective November 4, 2013: Automated Email Notification and Delivery of OD Files (96-Well Plasmid Preparation Service)

Posted on November 4, 2013

Dear DNA Core Customers,

Effective immediately, the CCIB DNA Core Facility will send out automated emails to its customers to inform when 96-well Plasmid DNA Preparation Orders are completed and ready to be shipped back via Courier Service (shipment option currently for internal customers only). The file(s) with the corresponding quantitation data (OD260, OD280, 260/280, DNA concentration) will be included as an attachment.

Sincerely,

The CCIB DNA Core Staff

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Effective October 1, 2013: FY14 Service Fees

Posted on September 24, 2013

Dear Clients:

We would like to update you on our FY14 service fee structure, which has now been set after discussion with Partners Research Finance Management and will be effective October 1, 2013. The new service fees, which entail increases in some service costs, reflect modest increases in the associated reagent and labor costs. We are pleased to announce that the fees for our Oligonucleotide Synthesis and Mouse Genotyping services remain the same as in the previous fiscal year. Wherever fees have been increased, these increases were mandated by Partners policies that dictate that Cores recover their operating costs while not generating revenues in excess of their operating costs.

Throughout the previous fiscal year, the Core has strongly engaged in continuous process improvement efforts to further increase the value of existing services and to rollout new Custom Molecular Biology & Sequencing services. Also in the new fiscal year, the Core will stay committed to evaluating and developing new services in order to meet the changing research needs of the Partners research community.

Thank you for your patronage!!!

Sincerely,

The CCIB Team

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Effective June 30, 2013: Online Access to Oligonucleotide Specification Info

Posted on June 30 2013

Dear DNA Core Customers,

We are pleased to announce that effective immediately the CCIB DNA Core Facility will provide online access to oligonucleotide specifications for all DNA synthesis orders. Once orders are complete, a link will appear on the DNA synthesis order status page allowing users to download the specifications including sequence, molecular weight, yield, molarity, etc.

Sincerely,
The CCIB DNA Core Staff

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Effective May 10, 2013: Launch of Long-Read DNA Sequencing Service

Posted on April 25, 2013

Dear DNA Core Customers,

We are pleased to announce that effective immediately the DNA Core Facility will be providing a Long-Read DNA Sequencing Service as part of its Custom Molecular Biology & Sequencing Service portfolio. Compared to our standard sequencing protocol (typical Q20 read length > 700 bases), this new service delivers an additional 200 bases on average and can yield up to 1000 Q20 bases per sample. At this point in time, a minimum of 12 samples has to be submitted to take advantage of this service. Turnaround is between 24 and 48 hours. Please note that the rates for the new long-read service (detailshere) differ from those of our standard sequencing services and reflect slightly increased costs due to the implementation of a separate workflow, increased instrument time, and processing of partially filled plates.

Sample Submission for Long-Read Sequencing:

Please select the Long Read Sequencing option from the order menu under the Sequencing tab of our website and complete the submission sheet using the same guidelines that are in place for standard read sequencing orders.

Looking very much forward to process your orders!

Sincerely,
The CCIB DNA Core

Effective February 1, 2013: Revised Sequencing Workflow

Posted on January 15, 2013

Dear MGH DNA Core Client:

In the context of our continuous process improvement efforts, we are implementing a revised sequencing workflow on February 1, 2013. As a result of this process change,sequencing ordersas well asplasmid preparations for sequencingcan contain amaximum of 95 samples per plate. Effective February 1, 2013, well positionH12must be left empty for all plate orders. Full plate submissions of 95 samples will still be charged at the current rates. Thank you for helping us to serve you even better!

The MGH DNA Core

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MGH Holiday Hours: Martin Luther King Jr.

Posted on January 15, 2013

The MGH DNA Core Facility will be closed Monday, January 21, 2013 in honor of Martin Luther King Jr.

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Effective February 1, 2013: Revised Sequencing Workflow

Posted on January 14, 2013

In the context of our continuous process improvement efforts, we are implementing a revised sequencing workflow on February 1, 2013. As a result of this process change, sequencing orders as well as plasmid preparations for sequencing can contain a maximum of 95 samples per plate. Effective February 1, 2013, well position H12 must be left empty for all plate orders. Full plate submissions of 95 samples will still be charged at the current rates. Thank you for helping us to serve you even better!

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Update on FY13 Service Fees and New Services

Posted on December 18, 2012

We would like to inform you about our new and enhanced services we have begun to offer and our FY13 service fee structure, which has now been set after discussion with Partners Research Finance Management and will be effective January 1, 2013. These fees, which entail increases in some service costs, reflect modest increases in some reagent and labor costs. We are pleased to announce that the fees for our bulk sequencing, bulk microsatellite analysis and 96-well plasmid preparation services remain the same as in the previous fiscal year. Wherever fees have been increased, these increases were mandated by Partners policies that dictate that Cores recover their operating costs while not generating revenues in excess of their operating costs.

As a result of the Core's continuous process improvement efforts and its commitment to constantly evaluate and develop new services in order to meet the changing research needs of the Partners research community in a timely manner, we are pleased to announce the launch of our new Custom Molecular Biology and Sequencing Services that include our previous Plasmid Verification and Primer Walking Services, midi- and maxi-scale plasmid DNA preparations as well as special sequencing protocols. A detailed description of our new custom service portfolio will be provided on our new and improved website which we are planning to launch in February 2013. Until then, please contact Dr. Nicole Stange-Thomann, Core Director, directly for more information (email nstange-thomann@ccib.mgh.harvard.edu).

In January 2013, we will also send out a survey to kindly ask for your valuable feedback on the DNA Core's overall performance as well as the quality of its individual services and your suggestions for further improvements and additional new services.

The MGH DNA Core is committed to providing timely help to investigators in solving critical and diverse biological/biomedical questions by providing a portfolio of state-of-the-art molecular biology and genomics services, specialized expertise, detailed advice and individual support. We are looking forward to support your research needs through FY13 and beyond.

Thank you for choosing the MGH DNA Core as your research partner!

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