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Previous Announcements

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Holiday Closure Announcement

Posted on May 24, 2022

Dear Core Users,

Our facility will be closed on Monday, May 30th, 2022 in observance of Memorial Day. Our courier service will not be operating, and our on-site dropbox will be only accessible with a key card as the entrance to the building will be locked. Please see below for details.

  • Sanger Sequencing / Fragment Analysis (Microsatellite/MLPA)

    Friday, 5-27-22 - Samples received by 12:00 PM will be processed, and data will be posted on Tuesday, 5-31-2022.

  • Next-Gen Services (Complete Plasmid, Amplicon, CRISPR and Viral Sequencing)

    All samples submitted for the May 25th cycle may experience a 1 day delay in receipt of results. As soon as the data becomes available, we will send out email notifications.

  • Mouse Genotyping

    Tuesday, 5-31-2022 - Results for all Mouse Genotyping orders received by Tuesday morning will be available on Friday, 6-3-2022.

  • 96-well Plasmid DNA Preparation

    Friday, 5-27-22 - Orders placed on Friday will be completed by Tuesday, 5-31-2022.

The entire CCIB DNA Core team wishes you a happy and safe holiday weekend.

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MGH CCIB DNA Core Facility Closed for Presidents' Day (February 21, 2022)

Posted on February 14, 2022

Dear Core Users,

In observance of Presidents' Day, the DNA Core Facility will be closed on Monday, February 21, 2022. Our courier service will not be operating on this day, and samples will not be picked up from or delivered to our remote drop box locations.

Our on-site drop box at 38 Sidney Street (Cambridge, MA) will be accessible on this day. Please note that samples will be kept at ambient temperature until Tuesday morning, February 22.

If you need any assistance planning your orders with us, please don't hesitate to contact us.

Sincerely,
The MGH CCIB DNA Core Team

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MGH CCIB DNA Core Facility Closed for Martin Luther King Jr. Day (January 17, 2022)

Posted on January 11, 2022

Dear Core Users:

In observance of Martin Luther King, Jr Day, the DNA Core Facility will be closed on Monday, January 17, 2022. Our Courier service will not be operating on this day, and samples will not be picked up from or delivered to our remote drop box locations. Our on-site drop box at 38 Sidney Street (Cambridge, MA) will not be accessible on this day.

If you should need any help planning your orders with us, please don't hesitate to contact us.

Sincerely,
The CCIB DNA Core Team

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Holiday Closure Announcement

Posted on December 10, 2021

Dear Core Users,

Our facility will be closed on Friday, December 24 and on Friday, December 31 due to the Christmas and New Year's holidays. On both days, our courier service will not be operating, and our on-site drop box will only be accessible with a key card as the entrance to the building will be locked. Please see below for details.

Ragon Institute Researchers: If the internal glass door to the drop box area at the Ragon Institute is locked due to a holiday closure, our courier will not have access to the cooler on those days. Please check with Ragon facilities for scheduled closures in that area so you may plan accordingly.

  • Sanger Sequencing / Fragment Analysis (Microsatellite/MLPA)

    Thursday, 12-23-2021 - Samples received by 12:00 PM will be processed, and data will be posted on Monday, 12-27-2021

    Thursday, 12-30-2021 - Samples received by 12:00 PM will be processed, and data will be posted on Monday, 1-3-2022.

  • Next-Gen Services (Complete Plasmid, Amplicon, CRISPR and Viral Sequencing)

    Our December 22nd NGS cycle. Samples for this cycle will be accepted on December 20th, 21st,and 22nd.

    Our December 29th NGS cycle. Samples for this cycle will be accepted on December 27th, 28th and 29th. We recommend early submissions.

    All NGS samples submitted for the December 22nd and 29th cycles may experience a 1-2 day delay in receipt of results. As soon as the data becomes available, we will send out email notifications.

  • Mouse Genotyping

    Monday, 12-20-2021 - Results for all Mouse Genotyping orders received by Monday morning will be available on Thursday, 12-23-2021.

    Monday, 12-27-2021 - Results for all Mouse Genotyping orders received by Monday morning will be available on Thursday, 12-30-2021.

  • 96-well Plasmid DNA Preparation

    Thursday, 12-23-2021 - Orders placed on Thursday will be completed by Tuesday, 12-28-2021.

    Thursday, 12-30-2021 - Orders placed on Thursday will be completed by Tuesday, 01-04-2022.

The entire CCIB DNA Core team wishes you a safe and happy holiday season. We would also like to take this opportunity to thank you for your business this year. We look forward to contributing to your success in 2022!

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Thanksgiving Holiday Schedule

Posted on Novemeber 17, 2021

Dear Core Users:

In observance of the Thanksgiving holiday, our regular operations will be modified as follows:
The CCIB DNA Core will be closed Thursday, November 25 and Friday, November 26, 2021. Our Courier Service will not be operating on either day, and samples will not be picked up from any of our remote drop box locations. Direct sample drop-off at 38 Sidney Street is also not available on these days as the entrance to the main building will be locked. We will resume normal hours on Monday, November 29, 2021.

Please note that you might experience a delay of 2-3 business days in the processing of your samples due to the holiday break. If you have questions regarding your order, please contact us at dnacore@ccib.mgh.harvard.edu.

We wish you a very Happy Thanksgiving.
The CCIB DNA Core Team

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MGH CCIB DNA Core Facility Closed for Columbus Day (October 11, 2021)

Posted on October 6, 2021

Dear Core Users:

In observance of Columbus Day, the DNA Core Facility will be closed on Monday, October 11, 2021. Our Courier service will not be operating on this day, and samples will not be picked up from or delivered to our remote dropbox locations. Our on-site dropbox will be accessible on this day. Please note that samples will be kept at ambient temperature until Tuesday morning, October 12.

If you should need any help planning your orders with us, please don't hesitate to contact us.

Sincerely,

-The MGH CCIB DNA Core Team

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CCIB DNA Core Facility Closed for Labor Day

Posted on August 31, 2021

Dear Core Users,

In observance of Labor Day, the DNA Core Facility will be closed on Monday, September 6, 2021. Please note that our courier service will not be operating on this day. Samples will not be picked up from our remote dropbox locations, and orders will not be delivered to any dropbox. Our on-site dropbox will only be accessible with a key card as the entrance to the Clark Building (38 Sidney Street, Cambridge, MA) will be locked on this day.

If you should need any assistance planning your orders with us, please don't hesitate to contact us.

Wishing you a Happy Labor Day!

The CCIB DNA Core Staff

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Holiday Closure on Monday, July 5, 2021: Observance of Independence Day

Posted on June 23, 2021

The MGH CCIB DNA Core Facility will be closed on Monday, July 5th, 2021 in observance of Independence Day. Our Courier service will not be operating on this day, and samples will not be picked up from or delivered to our remote dropbox locations. Our onsite dropbox will only be accessible with a key card as the entrance to the Clark Building (Suite 100, 38 Sidney Street, Cambridge, MA) will be locked.

Service turnaround times may be slightly longer due to the holiday closure. We will do our best to process your orders as quickly as possible. If you should need any help planning your orders with us, please don't hesitate to contact us.

Wishing you a happy, safe 4th of July weekend!

~ The CCIB DNA Core Team

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Holiday Closure Announcement

Posted on May 20, 2021

Dear Core Users,

Our facility will be closed on Monday, May 31st, 2021 in observance of Memorial Day. Our courier service will not be operating, and our on-site dropbox will be only accessible with a key card as the entrance to the building will be locked. Please see below for details.

  • Sanger Sequencing / Fragment Analysis (Microsatellite/MLPA)

    Friday, 5-28-21 - Samples received by 12:00 PM will be processed, and data will be posted on Tuesday, 6-1-2019.

  • Next-Gen Services (Complete Plasmid, Amplicon, CRISPR and Viral Sequencing)

    All samples submitted for the May 26th cycle may experience a 1 day delay in receipt of results. As soon as the data becomes available, we will send out email notifications.

  • DNA Synthesis

    Thursday-Monday, 5-27-2021 - 5-31-2021 - All oligonucleotide orders placed on these days will experience a 1-2 day delay in delivery.

  • Mouse Genotyping

    Tuesday, 6-1-2021 - Results for all Mouse Genotyping orders received by Tuesday morning will be available on Friday, 6-4-2021.

  • 96-well Plasmid DNA Preparation

    Friday, 5-28-21 - Orders placed on Friday will be completed by Tuesday, 6-1-2021.

The entire CCIB DNA Core team wishes you a happy and safe holiday weekend.

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We're Hiring!

Posted on April 28, 2021

The MGH CCIB DNA Core has opened up a full-time position for a Senior Research Technologist. As a member of the DNA Core, the Senior Research Technologist will be responsible for the operational management of the Core's PCR-based Genotyping service and Next-Gen Sequencing service (Illumina Sequencing). If you know someone who would fit the bill, please spread the word!

Senior Research Technologist (Job Number 3154555)

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BWH Research Cores and Resources Fair on April 26th!

Posted on April 19, 2021

Join us at this year's BWH Research Cores and Resources Fair! Monday, April 26th from 12:00 - 1:00 PM

The Brigham Research Institute is sponsoring a virtual Cores and Resources Fair which will feature research core facilities/resources, and provide an opportunity for the BWH research community to learn more about resources available to them as well as for cores to connect with researchers. This event is open to the entire BWH community - all researchers and research support staff who are interested in learning more about the prolific BWH and MGB core facilities are encouraged to attend. The event is also open to all MGB affiliated employees.
You can register and find more information on the cores/resources by clicking here.

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MGH CCIB DNA Core Facility Closed for Presidents' Day (February 15, 2021)

Posted on February 9, 2021

In observance of Presidents' Day, the DNA Core Facility will be closed on Monday, February 15, 2021. Our courier service will not be operating on this day, and samples will not be picked up from or delivered to our remote drop box locations.

Our on-site drop box at 38 Sidney Street (Cambridge, MA) will be accessible on this day. Please note that samples will be kept at ambient temperature until Tuesday morning, February 16.

If you need any assistance planning your orders with us, please don't hesitate to contact us.

Sincerely,
-The MGH CCIB DNA Core Team

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MGH CCIB DNA Core Facility Closed for Martin Luther King Jr. Day (January 18, 2021)

Posted January 11, 2021

Dear Core Users,

In observance of Martin Luther King, Jr Day, the DNA Core Facility will be closed on Monday, January 18, 2021. Our Courier service will not be operating on this day, and samples will not be picked up from or delivered to our remote drop box locations.

Our on-site drop box at 38 Sidney Street (Cambridge, MA) will NOT be accessible on this day. If you should need any help planning your orders with us, please don't hesitate to contact us.

Sincerely,
The CCIB DNA Core Team

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Holiday Closure Announcement

Posted on December 16, 2020

Dear Core Users,

Our facility will be closed on Friday, December 25 and on Friday, January 1 due to the Christmas and New Year's holidays. On both days, our courier service will not be operating, and our on-site dropbox will only be accessible with a key card as the entrance to the building will be locked. Please see below for details.

On Thursday, December 24th and Thursday, December 31st, the front and back doors to our main facility at 38 Sidney Street in Cambridge will be locked. However, we will be open until 3:00pm on these days. Please call our customer service number at 617-726-5982 or 617-726-0074 if you plan to drop off samples at this location on December 24th or December 31st.

Ragon Institute Researchers: If the internal glass door to the dropbox area at the Ragon Institute is locked on Christmas Eve or New Year's Eve, our courier will not have access to the cooler on those days. Please check with Ragon Facilities Staff for scheduled closures in that area so you may plan accordingly.

  • Sanger Sequencing / Fragment Analysis (Microsatellite/MLPA)

    Thursday, 12-24-2020 - Samples received by 12:00 PM will be processed, and data will be posted on Monday, 12-28-2020

    Thursday, 12-31-2020 - Samples received by 12:00 PM will be processed, and data will be posted on Monday, 1-4-2021.

  • Next-Gen Services (Complete Plasmid, Amplicon, CRISPR and Viral Sequencing)

    Our December 23rd NGS cycle. Samples for this cycle will be accepted on December 21st,22nd and 23rd.

    Our December 30th NGS cycle. Samples for this cycle will be accepted on December 28th, 29th and 30th. We recommend early submissions.

    All NGS samples submitted for the December 23rd and 30th cycles may experience a 1-3 day delay in receipt of results. As soon as the data becomes available, we will send out email notifications.

  • DNA Synthesis

    Tuesday, 12-22-2020 through Friday, 1-1-2021 - All oligonucleotide orders placed on these days will be delivered to our remote dropboxes with a 2-3 day delay. Oligos will be outsourced to IDT.

  • Mouse Genotyping

    Monday, 12-21-2020 - Results for all Mouse Genotyping orders received by Monday morning will be available on Thursday, 12-24-2020.

    Monday, 12-28-2020 - Results for all Mouse Genotyping orders received by Monday morning will be available on Thursday, 12-31-2020.

  • 96-well Plasmid DNA Preparation

    Thursday, 12-24-2020 - Orders placed on Thursday will be completed by Tuesday, 12-29-2020.

    Thursday, 12-31-2020 - Orders placed on Thursday will be completed by Tuesday, 01-05-2021.

The entire CCIB DNA Core team wishes you a safe and happy holiday season. We would also like to take this opportunity to thank you for your business this year. We look forward to contributing to your success in 2021!

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Thanksgiving Holiday Schedule

Posted on November 16, 2020

Dear Core Users,

In observance of the Thanksgiving holiday, our regular operations will be modified as follows:
The CCIB DNA Core will be closed Thursday, November 26 and Friday, November 27, 2020. Our courier service will not be operating on either day, and samples will not be picked up from any of our remote dropbox locations. Direct sample drop-off at 38 Sidney Street is also not available on these days as the entrance to the main building will be locked. We will resume normal hours on Monday, November 30, 2020.

Please note that you might experience at delay of 2-3 business days in the processing of your samples due to the holiday break. If you have questions regarding your order, please contact us at dnacore@ccib.mgh.harvard.edu.

We wish you a very Happy Thanksgiving.

-The MGH CCIB DNA Core Team

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We're Hiring

Posted on November 17, 2020

We are looking for a new team member with 16S Sequencing experience who can learn quickly, strive in a fast-paced environment, and is excited to learn new technologies. If this sounds like you, please use the link below to apply for our open position. Experience in research automation, molecular biology, Illumina sequencing and/or 16S sequencing/analysis are a plus. If you know someone who would fit the bill, please spread the word!

Research Technologist (Job Number 3138481)

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MGH CCIB DNA Core Facility Closed for Columbus Day (October 12, 2020)

Posted on October 6, 2020

Dear Core Users:

In observance of Columbus Day, the DNA Core Facility will be closed on Monday, October 12, 2020. Our Courier service will not be operating on this day, and samples will not be picked up from or delivered to our remote drop box locations. Our on-site drop box will be accessible on this day. Please note that samples will be kept at ambient temperature until Tuesday morning, October 13.

If you should need any help planning your orders with us, please don't hesitate to contact us.

Sincerely,

-The MGH CCIB DNA Core Team

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New Pricing Structure for NGS Services

Posted on September 11, 2020

We are pleased to announce a change to our pricing structure for our NGS-based services. Beginning October 1st 2020, orders of 48-95 samples in plate format (filled by rows) will receive a discounted rate. Orders of 96 samples in plate format will continue to receive the full plate 'bulk' rate and orders of 1-47 samples will receive the individual sample rate.

We are committed to advancing research productivity and generating the highest quality data. We hope our new pricing option supports a large number of innovative projects.

-The MGH CCIB DNA Core Team

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Effective October 1, 2020: FY'21 Service Fees

Posted on September 17, 2020

Dear Core Users:

Our FY'21 service fee structure has now been set after discussion with MGB Research Finance Management and goes into effect as of October 1, 2020. The new service fees reflect small increases in the costs of reagents, consumables and labor for specific services. These fees support both our continuous process improvement efforts and the implementation of additional service features.

All orders that started being processed this month but are completed on or after October 1, 2020, will be invoiced at current (FY'20) pricing. Orders that are placed close to the end of September but are not processed before October 1, 2020, will be invoiced according to our new FY'21 pricing structure.

We appreciate your past patronage and look forward to serving your future research needs.

-The MGH CCIB DNA Core Team

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CCIB DNA Core Facility Closed for Labor Day

Posted on September 2, 2020

Dear Core Users,

In observance of Labor Day, the DNA Core Facility will be closed on Monday, September 7, 2020. Please note that our courier service will not be operating on this day. Samples will not be picked up from our remote dropbox locations, and orders will not be delivered to any dropbox. Our on-site dropbox will be only accessible with a key card as the entrance to the Clark Building (38 Sidney Street, Cambridge, MA) will be locked on this day.

If you should need any assistance planning your orders with us, please don't hesitate to contact us.

Wishing you a Happy Labor Day!

Sincerely,
The CCIB DNA Core Staff

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Holiday Closure on Friday, July 3, 2020: Observance of Independence Day

Posted on July 2, 2020

The MGH CCIB DNA Core Facility will be closed on Friday, July 3rd, 2020 in observance of Independence Day. Our Courier service will not be operating on this day, and samples will not be picked up from or delivered to our remote dropbox locations. Our onsite dropbox will only be accessible with a key card as the entrance to the Clark Building (Suite 100, 38 Sidney Street, Cambridge, MA) will be locked.

Service turnaround times may be slightly longer due to the holiday closure. We will do our best to process your orders as quickly as possible.

If you should need any help planning your orders with us, please don't hesitate to contact us.

Wishing you a happy, safe 4th of July weekend!

~ The Core Team

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USER ALERT!

Scheduled Server Maintenance: CCIB DNA core site unavailable Friday July 10 from 9pm until Saturday July 11 at noon.

Posted on July 10, 2020

Dear Users,

On Friday, July 10, 2020 at 9pm, we will be shutting down the CCIB DNA core site for scheduled maintenance. The site will be unavailable until Saturday, July 11, 2020 at noon.

Please accept our apologies for the inconvenience.

~ The CCIB DNA Core Team

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Important Information Regarding the CCIB DNA Core Schedule!

Updated on June 7, 2020

Dear Core Users:

The CCIB DNA Core is open. Our facility will continue to operate with a reduced staff until further notice. Turnaround times have been extended slightly. Our courier service has resumed to all regular locations. Please visit this announcement page often for updates. We will strive to provide advanced notice of future schedule/service adjustments.

  • Next-Gen Services (Complete Plasmid, Amplicon, CRISPR and Viral Sequencing)

    All four of our NGS-based services are available. NEW: we will begin processing on Tuesdays and Wednesdays. You may send your samples early. Please expect results to be posted 1-2 weeks from the Tues/Wed start date. Larger orders (>50 samples may take longer, depending on overall volumes). Please contact the Core Director at aavery@ccib.mgh.harvard.edu to request processing of full plates.

  • Sanger Sequencing / DNA Fragment Analysis (Microsatellite/MLPA)

    Our Sanger Sequencing and Fragment Analysis services are available. Please expect results within 1-2 business days.

  • DNA Synthesis

    Researchers may order oligos directly through our website. Orders will be outsourced to IDT until further notice. Please expect a 1-2 day delay in delivery of your order via our courier.

  • Mouse Genotyping

    Our weekly Mouse Genotyping service has resumed. Results will be available within 5-6 business days.

  • 96-well Plasmid DNA Preparation

    Our Plasmid DNA Preparation service is temporarily reserved for special requests only. Please contact the Core Director at aavery@ccib.mgh.harvard.edu to schedule processing.

  • Custom Automation

    Please contact the Core Director for scheduling.

If you need any assistance planning your orders with us, please don't hesitate to contact us. We apologize for any inconvenience and thank you for your patience during this time.

Sincerely,
-The MGH CCIB DNA Core Team

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Important Information Regarding the CCIB DNA Core Schedule!

Updated on March 27, 2020

Dear Core Users:

The MGH CCIB DNA Core is processing critical samples directly related to Covid-19 studies only. To cooperate with the recommendations to support the response to Coronavirus, the facility will operate with a reduced staff until further notice. Please visit this announcement page often for updates. We will strive to provide advanced notice of future schedule/service adjustments.

The MGH CCIB DNA Courier Service will temporarily cease operating after March 20th. The main facility may remain open for limited services. You may schedule a visit for pick up/delivery at our facility at 38 Sidney St. Cambridge MA. Please contact us First!

  • Next-Gen Services (Complete Plasmid, Amplicon, CRISPR and Viral Sequencing)

    All four of our NGS-based services will be available for priority samples related to Covid-19 studies only. Please hold your regular orders until we resume full operations. Expect extended turnaround times (results for critical Covid-19 samples will be posted 2-4 weeks from the Wednesday start date). Please contact the Core Director at aavery@ccib.mgh.harvard.edu to request processing of full plates.

  • Sanger Sequencing / DNA Fragment Analysis (Microsatellite/MLPA)

    Our Sanger Sequencing and Fragment Analysis Services are suspended. Please contact us if you have critical samples related to Covid-19 studies.

  • DNA Synthesis

    While our courier service is temporarily suspended, we suggest researchers order directly from IDT or other provider.

  • Mouse Genotyping

    The Mouse Genotyping service will be reduced to bimonthly, with lower capacity for samples. Please prioritize your samples. The next cycle will start on March 16th, followed by March 30th.

  • 96-well Plasmid DNA Preparation

    Our Plasmid DNA Preparation service is temporarily reserved for special requests only. Please contact the Core Director at aavery@ccib.mgh.harvard.edu to schedule processing.

  • Custom Automation

    Projects may be suspended for 6-8 weeks.

If you need any assistance planning your orders with us, please don't hesitate to contact us. We apologize for any inconvenience and thank you for your patience during this time.

Sincerely,
-The MGH CCIB DNA Core Team

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New Sample Pick-up Time for Charlestown Location

Posted on February 24, 2020

Dear Charlestown Researchers:

The CCIB DNA Core would like to make a new recommendation for sample drop off at our Charlestown location. The courier will pick up samples anytime between 10:30am and 11:00am, Monday-Friday. We have not changed our courier service provider. However, a 10:30am pick up may occur occasionally, and without notice, in the case of a substitute driver.

Please place your samples inside the cooler which is inside the refrigerator located at Bldg CNY149 room 6133, at the corner of room 6140, East side.

If you need any assistance planning your orders with us, please don't hesitate to contact us.

Sincerely,
-The MGH CCIB DNA Core Team

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MGH CCIB DNA Core Facility Closed for Presidents' Day (February 17, 2020)

Posted on February 7, 2020

Dear Core Users:

In observance of Presidents' Day, the DNA Core Facility will be closed on Monday, February 17, 2020. Our courier service will not be operating on this day, and samples will not be picked up from or delivered to our remote drop box locations.

Our on-site drop box at 38 Sidney Street (Cambridge, MA) will not be accessible on this day.

If you need any assistance planning your orders with us, please don't hesitate to contact us.

Sincerely,
-The MGH CCIB DNA Core Team

________________________________________________

MGH CCIB DNA Core Facility Closed for Martin Luther King Jr. Day (January 20, 2020)

Posted January 9, 2020

Dear Core Users,

In observance of Martin Luther King, Jr Day, the DNA Core Facility will be closed on Monday, January 20, 2020. Our Courier service will not be operating on this day, and samples will not be picked up from or delivered to our remote drop box locations.

Our on-site drop box at 38 Sidney Street (Cambridge, MA) will NOT be accessible on this day.

If you should need any help planning your orders with us, please don't hesitate to contact us.

Sincerely,
The Core Staff

________________________________________________

Holiday Closure Announcement

Posted on December 17, 2019

Dear Core Users,

Our facility will be closed on Wednesday, December 25 and on Wednesday, January 1, 2019 due to Christmas and New Year's holidays. On both days, our courier service will not be operating, and our on-site dropbox will be only accessible with a key card as the entrance to the building will be locked. Please see below for details.

On Tuesday, December 24th and Tuesday, December 31st, the front and back doors to our main facility at 38 Sidney Street in Cambridge will be locked. However, we will be open until 3pm on these days. Please call our customer service number at 617-726-5982 or 617-726-0074 if you plan to drop off samples at this location on December 24th or December 31st.

Ragon Institute Researchers: If the internal glass door to the dropbox area at the Ragon Institute is locked on Christmas Eve or New Year's Eve, our courier will not have access to the cooler on those days. Please check with Ragon Facilities Staff for scheduled closures in that area so you may plan accordingly.

  • Sanger Sequencing / Fragment Analysis (Microsatellite/MLPA)

    Tuesday, 12-24-2019 - Samples received by 12:00 PM will be processed, and data will be posted on Thursday, 12-26-2019

    Tuesday, 12-31-2019 - Samples received by 12:00 PM will be processed, and data will be posted on Thursday, 1-2-2020.

  • Next-Gen Services (Complete Plasmid, Amplicon, CRISPR and Viral Sequencing)

    Our December 25th NGS cycle will begin on December 23rd. Samples will be accepted on December 23rd, 24th and 26th.

    Our January 1st NGS cycle will begin On December 30th. Samples will be accepted on December 30th, 31st and January 2nd. We recommend early submissions.

    All NGS samples submitted for the December 18th, 25th and January 1st cycles may experience a 1-3 day delay in receipt of results. As soon as the data becomes available, we will send out email notifications.

  • DNA Synthesis

    Friday, 12-20-2019 through Thursday, 12-26-2019 - All oligonucleotide orders placed on these days will be delivered to our remote dropboxes with a 2-3 day delay. Oligos will be outsourced to IDT due to reduced staff at the Core.

    Friday, 12-27-2019 through Tuesday, 1-1-2020 - All oligonucleotide orders placed on these days will be delivered to our remote dropboxes with a 1-day delay.

  • Mouse Genotyping

    Monday, 12-23-2019 - Results for all Mouse Genotyping orders received by Monday morning will be available on Friday, 12-27-2019.

    Monday, 12-30-2019 - Results for all Mouse Genotyping orders received by Monday morning will be available on Friday, 1-3-2020.

  • 96-well Plasmid DNA Preparation

    Tuesday, 12-24-2019 - Orders placed on Tuesday will be completed by Friday, 12-27-2019.

    Tuesday, 12-31-2019 - Orders placed on Tuesday will be completed by Friday, 01-03-2020.


    The entire CCIB DNA Core team wishes you a safe and happy holiday season. We would also like to take this opportunity to thank you for your business this year. We look forward to contributing to your success in 2020!

    ________________________________________________

    Thanksgiving Holiday Schedule

    Posted on November 15, 2019

    Dear Core Users,

    In observance of the Thanksgiving holiday, our regular operations will be modified as follows: The CCIB DNA Core will be closed Thursday, November 28 and Friday, November 29, 2019. Our Courier Service will not be operating on either day, and samples will not be picked up from any of our remote dropbox locations. Direct sample drop-off at 38 Sidney Street is also not available on these days as the entrance to the main building will be locked. We will resume normal hours on Monday, December 2, 2019.

    Please note that you might experience at delay of 1-3 business days in the processing of your samples due to the holiday break. If you have questions regarding your order, please contact us at dnacore@ccib.mgh.harvard.edu.

    We wish you a very Happy Thanksgiving.

    Sincerely,
    ~ The CCIB DNA Core Team

    ________________________________________________

    WE ARE HIRING!

    Posted on November 12, 2019

    We are looking for a new team member who can learn quickly, strive in a fast-paced environment, and is excited to learn new technologies. If this sounds like you, please use the link below to apply for our open position. Experience in research automation, molecular biology, Illumina sequencing and/or 16S sequencing/analysis are a plus. If you know someone who would fit the bill, please spread the word!

    Research Technician (Job ID: 3106117)

    ________________________________________________

    MGH CCIB DNA Core Facility Closed for Columbus Day (October 14, 2019)

    Posted on October 8, 2019

    Dear Core Users:

    In observance of Columbus Day, the DNA Core Facility will be closed on Monday, October 14, 2019. Our Courier service will not be operating on this day, and samples will not be picked up from or delivered to our remote dropbox locations. Our on-site dropbox will be accessible on this day. Please note that samples will be kept at ambient temperature until Tuesday morning, October 15.

    If you should need any help planning your orders with us, please don't hesitate to contact us.

    Sincerely,

    -The MGH CCIB DNA Core Team

    ________________________________________________

    Effective October 1, 2019: FY'20 Service Fees

    Posted on September 20, 2019

    Dear Users,

    After discussion with Partners Research Finance Management, our FY'20 service fee structure has now been finalized and will go into effect as of October 1, 2019. We are pleased to announce that our Sanger and bulk NGS-based DNA Sequencing service fees will remain the same for FY'20, with no increase. Our individual tube NGS-based services will decreased slightly to reflect a recent process improvement. The cost savings is being passed onto you, our valued clients.

    These fees support our continuous process improvement efforts and the implementation of additional and/or improved service features. The changes are mandated by Partners policies, which dictate that cores recover their operating costs without generating excess revenue.

    All orders that begin processing in September but complete on or after October 1, 2019 will be invoiced at current (FY'19) pricing. Orders that are placed close to the end of September but are not processed before October 1, 2019 will be invoiced according to our new FY'20 pricing structure.

    We appreciate your past patronage and look forward to serving your future research needs.

    Sincerely,
    ~ The CCIB DNA Core Team

    ________________________________________________

    CCIB DNA Core Facility Closed for Labor Day (September 2, 2019)

    Posted on August 22, 2019

    Dear Users,

    In observance of Labor Day, the DNA Core Facility will be closed on Monday, September 2, 2019. Please note that our courier service will not be operating on this day. Samples will not be picked up from our remote dropbox locations, and orders will not be delivered to any dropbox. Our on-site dropbox will only be accessible with a key card as the entrance to the Clark Building (38 Sidney Street, Cambridge, MA) will be locked on this day.

    If you should need any assistance planning your orders with us, please don't hesitate to contact us.

    Wishing you a Happy Labor Day!
    ~ The CCIB DNA Core Team

    ________________________________________________

    NEW on our Website: Convenient 'GET A QUOTE' Feature!

    Posted on July 2, 2019

    Dear Users,

    We added a new GET A QUOTE feature to our website. Simply click the button displayed at the top of our page and complete the form. Your custom quote will be emailed to you immediately. We hope you find this new feature useful!

    If you have any questions or comments, please leave us your thoughts in our feedback form. We welcome your suggestions.

    Sincerely,
    -The MGH CCIB DNA Core Team

    ________________________________________________

    Holiday Closure on Thursday, July 4, 2019: Observance of Independence Day

    Posted on June 28, 2019

    The MGH CCIB DNA Core Facility will be closed on Thursday, July 4th, 2019 in observance of Independence Day. Our Courier service will not be operating on this day, and samples will not be picked up from or delivered to our remote dropbox locations. Our onsite dropbox will be only accessible with a key card as the entrance to the Clark Building (Suite 100, 38 Sidney Street, Cambridge, MA) will be locked.

    Service turnaround times may be slightly longer due to the holiday closure. We will do our best to process your orders as quickly as possible.

    If you should need any help planning your orders with us, please don't hesitate to contact us.

    Wishing you a happy, safe 4th of July!

    Sincerely,
    ~ The CCIB DNA Core Team

    ________________________________________________

    MGH Research Core Day!

    Posted on June 19, 2019

    Please join the MGH Research Community on June 27, 2019 starting at 2pm in Charlestown Navy Yard-149 Conference Room A and the Atrium Area to learn more about the Cores at MGH!

    Light refreshments will be available, along with a raffle!

    ________________________________________________

    Holiday Closure Announcement

    Posted on May 17, 2019

    Dear Core Users,

    Our facility will be closed on Monday, May 27th, 2019 in observance of Memorial Day. Our courier service will not be operating, and our on-site dropbox will be only accessible with a key card as the entrance to the building will be locked. Please see below for details.

    • Sanger Sequencing / Fragment Analysis (Microsatellite/MLPA)

      Friday, 5-24-19 - Samples received by 12:00 PM will be processed, and data will be posted on Tuesday, 5-28-2019.

    • Next-Gen Services (Complete Plasmid, Amplicon, CRISPR and Viral Sequencing)

      All samples submitted for the May 22nd cycle may experience a 1 day delay in receipt of results. As soon as the data becomes available, we will send out email notifications.

    • DNA Synthesis

      Thursday-Monday, 5-23-2019 - 5-27-2019 - All oligonucleotide orders placed on these days will experience a 1-2 day delay in delivery.

    • Mouse Genotyping

      Tuesday, 5-28-2019 - Results for all Mouse Genotyping orders received by Tuesday morning will be available on Friday, 5-31-2019.

    • 96-well Plasmid DNA Preparation

      Friday, 5-24-19 - Orders placed on Friday will be completed by Tuesday, 5-28-2019.

    The entire CCIB DNA Core team wishes you a happy and safe holiday weekend.

    ________________________________________________

    MGH CCIB DNA Core Facility Closed for Presidents' Day (February 18, 2019)

    Posted on February 11, 2019

    Dear Core Users:

    In observance of Presidents' Day, the DNA Core Facility will be closed on Monday, February 18, 2019. Our courier service will not be operating on this day, and samples will not be picked up from or delivered to our remote drop box locations.

    Our on-site drop box at 38 Sidney Street (Cambridge, MA) will be accessible on this day. Please note that samples will be kept at ambient temperature until Tuesday morning, February 19.

    If you need any assistance planning your orders with us, please don't hesitate to contact us.

    Sincerely,
    -The MGH CCIB DNA Core Team

    ________________________________________________

    MGH CCIB DNA Core Facility Closed for Martin Luther King Jr Day (January 21, 2019)

    Posted on January 14, 2019

    Dear Users,

    In observance of Martin Luther King's Day, the DNA Core Facility will be closed on Monday, January 21, 2019. Our Courier service will not be operating on this day, and samples will not be picked up from or delivered to our remote drop box locations.

    Our on-site drop box at 38 Sidney Street (Cambridge, MA) will be accessible on this day. Please note that samples will be kept at ambient temperature until Tuesday morning, January 22.

    If you should need any help planning your orders with us, please don't hesitate to contact us.

    Sincerely,
    ~ The CCIB DNA Core Team

    ________________________________________________

    NEW on our Website: Convenient 'ORDER HISTORY' Feature!

    Posted on January 22, 2019

    Dear Users,

    We added a new ORDER HISTORY feature to our website. After you successfully log into your account, you will see a new button called "ORDER HISTORY" which will be displayed at the top of our webpage. Simply click this button and you will be able to view order numbers, fund information, order dates and the current status of all submissions placed within the last 4 years.

    If you have any questions or comments, please leave us your thoughts in our feedback form. We welcome your suggestions.

    Sincerely,
    ~ The CCIB DNA Core Team

    ________________________________________________

    Holiday Closure Announcement

    Posted on December 17, 2018

    Dear Core Users,

    Our facility will be closed on Tuesday, December 25 and on Tuesday, January 1, 2019 due to Christmas and New Year's holidays. On both days, our courier service will not be operating, and our on-site dropbox will be only accessible with a key card as the entrance to the building will be locked. Please see below for details.

    On Monday December 31st, the front and back doors to our main facility at 38 Sidney Street in Cambridge will be locked. We will be open until 3pm on this day. Please call our customer service number at 617-726-5982 or 617-726-0074 if you plan to drop off samples at this location on the Dec 31st.

    • Sanger Sequencing / Fragment Analysis (Microsatellite/MLPA)

      Monday, 12-24-2018 - Samples received by 12:00 PM will be processed, and data will be posted on Wednesday, 12-26-2018.

      Monday, 12-31-2018 - Samples received by 12:00 PM will be processed, and data will be posted on Wednesday, 1-2-2019.

    • Next-Gen Services (Complete Plasmid, Amplicon, CRISPR and Viral Sequencing)

      All samples submitted for the Dec 19th and 26th cycles may experience a 1-2 day delay in receipt of results. As soon as the data becomes available, we will send out email notifications.

    • DNA Synthesis

      Friday, 12-21-2018 through Thursday, 12-27-2018 - All oligonucleotide orders placed on these days will be delivered to our remote dropboxes with a 2-3 day delay. Oligos will be outsourced to IDT due to reduced staff at the Core.

      Friday, 12-28-2018 through Tuesday, 1-1-2019 - All oligonucleotide orders placed on these days will be delivered to our remote dropboxes with a 1-day delay.

    • Mouse Genotyping

      Monday, 12-24-2018 - Results for all Mouse Genotyping orders received by Monday morning will be available on Friday, 12-28-2018.

      Monday, 12-31-2018 - Results for all Mouse Genotyping orders received by Monday morning will be available on Friday, 1-4-2019.

      ________________________________________________

      USER ALERT!

      Scheduled Server Maintenance: Permanent Deletion of Old Data Files on Tuesday, January 1, 2019

      Posted on December 3, 2018

      Dear Users,

      On Tuesday, January 1, 2019, we will permanently remove all old sequencing data files from our server. We strongly encourage you to download all of your data that were generated at our core facility before January 1, 2018.

      Please accept our apologies for the inconvenience.

      ~ The CCIB DNA Core Team

      ________________________________________________

      Thanksgiving Holiday Schedule

      Posted on November 12, 2018

      Dear Core Users,

      In observance of the Thanksgiving holiday, our regular operations will be modified as follows: The CCIB DNA Core will be closed Thursday, November 22 and Friday, November 23, 2018. Our Courier Service will not be operating on either day, and samples will not be picked up from any of our remote dropbox locations. Direct sample drop-off at 38 Sidney Street is also not available on these days as the entrance to the main building will be locked. We will resume normal hours on Monday, November 26, 2018.

      Please note that you might experience 2 to 3 business days of delay in the processing of your samples due to the holiday break. If you have questions regarding your order, please contact us at dnacore@ccib.mgh.harvard.edu.

      We wish you a very Happy Thanksgiving.

      -The MGH CCIB DNA Core Team

      ________________________________________________

      MGH CCIB DNA Core Facility Closed for Columbus Day (October 8, 2018)

      Posted on October 2, 2018

      Dear Core Users:

      In observance of Columbus Day, the DNA Core Facility will be closed on Monday, October 8, 2018. Our Courier service will not be operating on this day, and samples will not be picked up from or delivered to our remote dropbox locations. Our on-site dropbox will be accessible on this day. Please note that samples will be kept at ambient temperature until Tuesday morning, October 9.

      If you should need any help planning your orders with us, please don't hesitate to contact us.

      Sincerely,

      -The MGH CCIB DNA Core Team

      ________________________________________________

      Effective October 1, 2018: FY'19 Service Fees

      Posted on September 13, 2018

      Dear Core Users:

      After discussion with Partners Research Finance Management, our FY'19 service fee structure has now been finalized and will go into effect as of October 1, 2018.

      We are pleased to announce that our individual tube Sanger and NGS-based DNA Sequencing service fees will remain the same for FY'19, with no increase. Our bulk rates and additional service fees will increase slightly to reflect increases in the costs of reagents, consumables and labor. These fees support our continuous process improvement efforts and the implementation of additional and/or improved service features. The changes are mandated by Partners policies, which dictate that cores recover their operating costs without generating excess revenue. We like to remind our valued customers to please budget for core services with an annual inflationary increase of 3-5%.

      All orders that begin processing in September but complete on or after October 1, 2018 will be invoiced at current (FY'18) pricing. Orders that are placed close to the end of September but are not processed before October 1, 2018 will be invoiced according to our new FY'19 pricing structure.

      We appreciate your past patronage and look forward to serving your future research needs.

      -The MGH CCIB DNA Core Team

      ________________________________________________



      CCIB DNA Core Facility Closed for Labor Day (September 3, 2018)

      Posted on August 29, 2018

      Dear Core Users,

      In observance of Labor Day, the CCIB DNA Core Facility will be closed on Monday, September 3, 2018. Please note that our courier service will not be operating on this day; samples will not be picked up from our remote dropbox locations, and orders will not be delivered to any dropbox. Our on-site drop box will be only accessible with a key card as the entrance to the Clark Building (38 Sidney Street, Cambridge, MA) will be locked on this day.

      If you should need any assistance planning your orders with us, please don't hesitate to contact us.

      Wishing you a Happy Labor Day!

      The CCIB DNA Core Staff

      ________________________________________________

      Holiday Closure on Wednesday, July 4, 2018: Observance of Independence Day


      Posted on June 21, 2018

      The MGH CCIB DNA Core Facility will be closed on Wednesday, July 4th, 2018 in observance of Independence Day.

      Our Courier service will not be operating on this day, and samples will not be picked up from or delivered to our remote dropbox locations. Our onsite dropbox will be only accessible with a key card as the entrance to the Clark Building (Suite 100, 38 Sidney Street, Cambridge, MA) will be locked.

      Service turnaround times may be slightly longer due to the holiday closure. We will do our best to process your orders as quickly as possible. Please submit samples for our NGS services by 4pm on Thursday, July 5th. The cycle for this week will begin 1 day late.

      If you should need any help planning your orders with us, please don't hesitate to contact us.

      Wishing you a happy, safe 4th of July!

      ~ The Core Team

      ________________________________________________




      WE ARE CURRENTLY RECRUITING !!!




      Posted on June 7, 2018

      We are currently recruiting for the position of Research Technician. If you are looking for an exciting and fast-paced role within the MGH CCIB DNA Core and would like a 4-day work schedule (Wed-Sat), then this position may be perfect for you! Please use the link below to review the job description and apply.

      Research Technician (Job Number 3066343) - Four 10 hour shifts Wed- Sat

      ________________________________________________

      Holiday Closure Announcement

      Posted on May 21, 2018

      Dear Core Users,

      Our facility will be closed on Monday, May 28th, 2018 in observance of Memorial Day. Our courier service will not be operating, and our on-site dropbox will be only accessible with a key card as the entrance to the building will be locked. Please see below for details.

      • Sanger Sequencing / Fragment Analysis (Microsatellite/MLPA)

        Friday, 5-25-18 - Samples received by 12:00 PM will be processed, and data will be posted on Tuesday, 05-29-2018.

      • Next-Gen Services (Complete Plasmid, Amplicon, CRISPR and Viral Sequencing)

        All samples submitted for the May 23rd cycle may experience a 1-2 day delay in receipt of results. As soon as the data becomes available, we will send out email notifications.

      • DNA Synthesis

        Thursday-Monday, 5-24-2018 - 5-28-2018 - All oligonucleotide orders placed on these days will experience a 1-2 day delay in delivery.

      • Mouse Genotyping

        Tuesday, 05-29-2018 - Results for all Mouse Genotyping orders received by Tuesday morning will be available on Friday, 6-1-2018.

      • 96-well Plasmid DNA Preparation

        Friday, 05-28-2018 - Orders placed on Friday will be completed by Tuesday, 5-29-2018.

      The entire CCIB DNA Core team wishes you a happy and safe holiday weekend!

      ________________________________________________

      We are open on Patriot's Day



      Posted on April 13, 2018

      We will be fully operational on Monday, April 16, 2018. We'd like to wish the best to all the athletes participating in the Boston Marathon!

      -The MGH CCIB DNA Core Team

      ________________________________________________



      Normal Core Operations Have Resumed

      Posted on March 14, 2018

      Due to the severe weather and recent closure on March 13th, we have extended the deadline for NGS sample submissions this week. All samples received on Thursday, March 15th will be entered into this week's cycle. Some delays in sample processing and data delivery should be expected. We apologize for any inconvenience and thank you for your patience.

      If you should need any help planning your orders with us, please don't hesitate to contact us.

      Sincerely,
      The CCIB DNA CORE Team

      ________________________________________________



      Important Update: Winter Storm Closure

      Posted on March 13, 2018

      For the safety of our staff, the MGH CCIB DNA Core facility will remain closed today, March 13th. We have extended the deadline for NGS sample submissions. All samples received on Thursday the 15th will be entered into this week's cycle. Some delays in sample processing and data delivery should be expected. We apologize for any inconvenience and thank you for your patience. We hope you all stay safe!

      If you should need any help planning your orders with us, please don't hesitate to contact us.

      Sincerely,
      The CCIB DNA CORE Team

      ________________________________________________

      The remodel of our lobby

      Posted on February 27, 2018

      The remodel of our lobby at 38 Sidney Street is nearly complete! We hope all of our clients who personally deliver samples to our main location will enjoy the new look!

      This major renovation had to be carefully coordinated to avoid any building closures. The Core remained fully operational during the construction. Thank you for your patience and patronage during this time.

      -The MGH CCIB DNA Core Team

      ________________________________________________

      We Are Keeping Up with Your Demand!



      Posted on February 1, 2018

      Submissions for our specialized NGS services (Complete Plasmid Sequencing, Whole Amplicon, CRISPR Amplicon and Viral Genome Sequencing) have been increasing steadily! We are pleased to continue to offer the same fast turnaround time due to our streamlined protocols and highly skilled staff. Thank you for your continued support of the CCIB DNA Core!

      Remember to Like us and Follow us! Simply click on the social media buttons in the footer section of our webpages, and you will be automatically directed to our networking sites.

      ________________________________________________



      MGH CCIB DNA Core Facility Closed for Presidents' Day (February 19, 2018)


      Posted on February 1, 2018

      Dear Core Users,

      In observance of Presidents' Day, the DNA Core Facility will be closed on Monday, February 19, 2018. Our courier service will not be operating on this day, and samples will not be picked up from or delivered to our remote drop box locations.

      Our on-site drop box at 38 Sidney Street (Cambridge, MA) will be accessible on this day. Please note that samples will be kept at ambient temperature until Tuesday morning, February 20.

      If you should need any help planning your orders with us, please don't hesitate to contact us.

      ________________________________________________


      MGH CCIB DNA Core Facility Closed for Martin Luther King's Day (January 15, 2018)

      Posted on January 9, 2018

      Dear Core Users,

      In observance of Martin Luther King's Day, the DNA Core Facility will be closed on Monday, January 15, 2018. Our Courier service will not be operating on this day, and samples will not be picked up from or delivered to our remote drop box locations.

      Our on-site drop box at 38 Sidney Street (Cambridge, MA) will be accessible on this day. Please note that samples will be kept at ambient temperature until Tuesday morning, January 16.

      If you should need any help planning your orders with us, please don't hesitate to contact us.

      Sincerely,

      The Core Staff

      ________________________________________________

      Important Update: Winter Storm Closing

      Posted on January 3, 2018

      The MGH CCIB DNA Core facility will close Thursday, January 4, 2018 at noon for the safety of our staff. Some delays in sample processing and data delivery should be expected.

      We are planning to reopen on Friday, January 5, 2018.

      Stay safe !

      ________________________________________________

      Holiday Closure Announcement

      Posted on December 15, 2017

      Dear Core Users,

      Our facility will be closed on Monday, December 25 and on Monday, January 1, 2018 due to Christmas and New Year's holidays. On both days, our courier service will not be operating, and our on-site dropbox will be only accessible with a key card as the entrance to the building will be locked. Please see below for details.

      • Sanger Sequencing / Fragment Analysis (Microsatellite/MLPA)

        Friday, 12-22-2017 - Samples received by 12:00 PM will be processed, and data will be posted on Tuesday, 12-26-2017.

        Friday, 12-29-2017 - Samples received by 12:00 PM will be processed, and data will be posted on Tuesday, 1-2-2018.

      • Next-Gen Services (Complete Plasmid, Amplicon, CRISPR and Viral Sequencing)

        All samples submitted for the Dec 20th and 27th cycles may experience a 1-2 day delay in receipt of results. As soon as the data becomes available, we will send out email notifications.

      • DNA Synthesis

        Thursday, 12-21-2017 - All oligonucleotide orders placed on this day will be delivered on Tuesday, 12-26-17.

        Friday, 12-22-2017 through Thursday, 12-28-2017 - All oligonucleotide orders will be outsourced to IDT. Dependent on IDT's shipping schedule, oligos will be delivered to our remote dropboxes with a 1-2 day delay.

      • Mouse Genotyping

        Tuesday, 12-26-2017 - Results for all Mouse Genotyping orders received by Tuesday morning will be available on Friday, 12-29-2017.

        Tuesday, 1-2-2018 - Results for all Mouse Genotyping orders received by Tuesday morning will be available on Friday, 1-5-2018.

      • 96-well Plasmid DNA Preparation

        Friday, 12-22-2017 - Orders placed on Friday will be completed by Tuesday, 12-26-2017.

        Friday, 12-29-2017 - Orders placed on Friday will be completed by Tuesday, 01-02-2018.

      The entire CCIB DNA Core team wishes you a safe and happy holiday season. We would also like to take this opportunity to thank you for your business this year. We look forward to contributing to your success in 2018!

      ________________________________________________

      USER ALERT!

      Scheduled Server Maintenance: Permanent Deletion of Old Data Files on Sunday, January 1, 2017

      Posted on December 4, 2017

      Dear Users,

      On Monday, January 1, 2018, we will permanently remove all old sequencing data files from our server. We strongly encourage you to download all of your data that were generated at our core facility before January 1, 2017.

      Please accept our apologies for the inconvenience.

      ~ The CCIB DNA Core Team

      ________________________________________________

      Thanksgiving Holiday Schedule

      Posted on November 15, 2017

      Dear Core Users,

      In observance of the Thanksgiving holiday, our regular operations will be modified as follows:

      The CCIB DNA Core will be closed Thursday, November 23 and Friday, November 24, 2017. Our Courier Service will not be operating on either day, and samples will not be picked up from any of our remote dropbox locations. Direct sample drop-off at 38 Sidney Street is also not available on these days as the entrance to the main building will be locked. We will resume normal hours on Monday, November 27, 2017.

      Please note that you might experience 2 to 3 business days of delay in the processing of your samples due to the holiday break. If you have questions regarding your order, please contact us at dnacore@ccib.mgh.harvard.edu.

      We wish you a very Happy Thanksgiving. Please enjoy this special time of year!

      ~ The MGH CCIB DNA Core Team

      ________________________________________________

      MGH CCIB DNA Core Facility Closed for Columbus Day (October 9, 2017)

      Posted on October 5, 2017

      Dear Core Users:

      In observance of Columbus Day, the DNA Core Facility will be closed on Monday, October 9, 2017. Our Courier service will not be operating on this day, and samples will not be picked up from or delivered to our remote dropbox locations.
      Our on-site dropbox will be accessible on this day. Please note that samples will be kept at ambient temperature until Tuesday morning, October 10.

      If you should need any help planning your orders with us, please don't hesitate to contact us.

      Happy Columbus Day!

      Sincerely,

      ~ The MGH CCIB DNA Core Team

      ________________________________________________

      Effective October 1, 2017: FY'18 Service Fees

      Posted on September 19, 2017

      Dear Core Users:

      Our FY'18 service fee structure has now been set after discussion with Partners Research Finance Management and goes into effect as of October 1, 2017. The new service fees reflect small increases in the costs of reagents, consumables and labor, and these fees support both our continuous process improvement efforts and the implementation of additional and/or improved service features, in particular for our various high-demand Next-Gen Sequencing applications. Although we would like to keep our current rates, these increases were mandated by Partners policies that dictate that Cores recover their operating costs while not generating revenues in excess of their operating costs. Please be assured that we have done our best to hold down costs for you but we do not want to compromise on quality. Our new rates guarantee that we can continue to provide the same level of quality and service that you have come to expect from us, and that we can continue to develop new service applications for you.

      All orders that started being processed this month but are completed on or after October 1, 2017, will be invoiced at current (FY'17) pricing. Orders that are placed close to the end of September but are not processed before October 1, 2017, will be invoiced according to our new FY'18 pricing structure.

      We appreciate your past patronage and look forward to serving your future research needs.

      ~ The MGH CCIB DNA Core Team

      ________________________________________________

      We have a new look and logo!

      Posted on September 12, 2017

      Notice anything new? We're proud and excited to reveal our new logo and our redesigned website to our users today.

      The primary objectives of our site development effort were focused on aesthetics and increasing the visibility of our research service portfolio. The new design also allows for streamlined menus and clear navigation.
      We hope you will like our new-look website!

      We would also like to thank everyone who spent time and energy to make this site what it is.

      For any questions, suggestions, feedback or comments, please e-mail us

      Thank You!
      The MGH CCIB DNA Core Team

      ________________________________________________



      LAUNCH OF OUR NEW WEBSITE !!!

      Posted on September 6, 2017

      We've redesigned our website with you in mind! After several months of hard work and dedication, we are now preparing for the official launch of our brand-new redesigned website on September 12, 2017.

      The primary objectives of our site development effort were focused on aesthetics and increasing the visibility of our research service portfolio. The new design also allows for streamlined menus and clear navigation.

      Looking forward to have you exploring the new site soon to learn more about our full spectrum of services!

      The MGH CCIB DNA Core Team

      ________________________________________________

      CCIB DNA Core Facility Closed for Labor Day
      (September 4, 2017)

      Posted on August 29, 2017

      Dear Core Users:

      In observance of Labor Day, the DNA Core Facility will be closed on Monday, September 4, 2017. Please note that our courier service will not be operating on this day; samples will not be picked up from our remote dropbox locations, and orders will not be delivered to any dropbox. Our on-site drop box will be only accessible with a key card as the entrance to the Clark Building (38 Sidney Street, Cambridge, MA) will be locked on this day.

      If you should need any assistance planning your orders with us, please don't hesitate to contact us.

      Wishing you a Happy Labor Day!

      The CCIB DNA Core Staff

      ________________________________________________



      New Next-Gen Sequencing Services !




      Posted on August 3, 2017

      The MGH CCIB DNA Core is pleased to announce the launch of two new specialized applications within its Next-Gen Sequencing portfolio. These new services are:

      1. Complete Amplicon Sequencing

      2. Viral Genome Sequencing

      For service details, please visit the corresponding new pages on our website. If you have any questions, please let us know.

      ________________________________________________




      WE ARE CURRENTLY RECRUITING !!!




      Posted on July 21, 2017

      We are currently recruiting for the positions of Research Technologist and Sr. Research Technologist. If you are looking for an exciting and fast-paced role within the MGH CCIB DNA Core, then one of these may suit you!

      Please use the links below to review the job descriptions and to apply for the open positions. If you know someone who would fit the bill, please spread the word!

      Research Technologist (Job Number 3040815)

      Senior Research Technologist (Job Number 3043178)

      ________________________________________________

      New Sample Dropbox in the New Research Building (NRB) of Harvard Medical School

      Posted on July 12, 2017

      Due to popular demand for our services, we have established a second sample dropbox in the Longwood Medical Area. Our new dropbox is located in the New Research Building (NRB) of Harvard Medical School (77 Louis Pasteur Avenue, ground floor, behind the main staircase at the Blackfan Street entrance).

      Samples will be picked up daily (Mon-Fri) at 8:15 AM.

      Courier service for the new dropbox will officially start on Monday, July 17, 2017. Please place your samples and a copy of your order form in the dropbox BEFORE 8:15 AM.

      Sincerely,
      The MGH CCIB DNA Core Team

      ________________________________________________

      Holiday Closure on Tuesday, July 4, 2017: Observance of Independence Day

      Posted on June 27, 2017

      The MGH CCIB DNA Core Facility will be closed on Tuesday, July 4, 2017 in observance of Independence Day.

      Our Courier service will not be operating on this day, and samples will not be picked up from or delivered to our remote dropbox locations. Our onsite dropbox will be only accessible with a key card as the entrance to the Clark Building (Suite 100, 38 Sidney Street, Cambridge, MA) will be locked.

      Service turnaround times may be slightly longer due to the holiday closure. We are doing our best to process your orders as quickly as possible.

      If you should need any help planning your orders with us, please don't hesitate to contact us.

      Wishing you a happy, safe 4th of July!

      ~ The Core Team

      ________________________________________________



      WE ARE HIRING !




      Posted on June 1, 2017

      We are looking for two new team members who can learn quickly, strive in a fast-paced environment, and are devoted towards highest customer satisfaction. If this sounds like you, please use the links below to apply for our open positions. If you know someone who would fit the bill, please spread the word!

      Research Technologist (Job Number 3040815)

      Research Technician II (Job Number 3040816)

      ________________________________________________

      Now Providing Daily Sample Pickup Service in the Longwood Medical Area!

      Posted on March 29, 2017

      We are pleased to announce that we are switching to a daily pickup service for our sample dropbox located in the new Brigham and Women's Building for Transformative Medicine at 60 Fenwood Road.

      The new daily schedule will commence on Thursday, March 30. Samples will be picked up Mon-Fri at 8:15 AM.

      The dropbox is located on the building' s ground floor, in the room next to the freight elevators (also accessible directly from the loading dock on Vining Street).

      Sincerely,

      The MGH CCIB DNA Core Team

      ________________________________________________

      Sponsored by the Brigham Research Institute: Cores and Resources Fair on Monday, June 19, at 12 PM in the BTM Café Atrium!

      Posted on June 18, 2017

      Dear Core Users, Members of the Partners Research Community,

      We are looking forward to chat with you about our diverse portfolio of service capabilities at our table during the Core Fair. Please stop by!

      Core Fair 12-2 PM

      Monday, June 19, 2017

      BTM Café Atrium (60 Fenwood Rd, 1st floor, Boston)


      Directions: Enter at 60 Fenwood Rd main entrance. Take the lobby staircase to the 1st floor. The BTM Café Atrium (open space) is across from the BTM Café.

      See you then!

      ~ The MGH CCIB DNA Core Team

      ________________________________________________

      MGH CCIB DNA Core Facility Closed for Memorial Day
      (May 29, 2017)

      Posted on May 22, 2017

      Dear Core Users,
      In observance of Memorial Day, the DNA Core Facility will be closed on Monday, May 29, 2017. Our Courier service will not be operating on this day, and samples will not be picked up from or delivered to our remote drop box locations. Our on-site drop box will be only accessible with a key card as the entrance to the Clark Building (38 Sidney Street, Cambridge, MA) will be locked.

      If you should need any help planning your orders with us, please don't hesitate to contact us.

      We hope you'll enjoy the Memorial Day Weekend!

      Sincerely,

      The MGH CCIB DNA Core Staff

      ________________________________________________

      Important Update: Winter Storm Closing

      Posted on March 14, 2017

      The MGH CCIB DNA Core facility is closed today to ensure the safety of our staff. Some delays in sample processing and data delivery should be expected. Samples will not be picked up from our remote dropboxes today.

      We are planning to reopen tomorrow, Wednesday, March 15, 2017.

      Stay safe !

      ________________________________________________

      Our 1st Sample Dropbox in the Longwood Medical Area!

      Posted on February 17, 2017

      We are pleased to announce that we now have a sample dropbox in the new Brigham and Women's Building for Transformative Medicine at 60 Fenwood Road.

      Our new dropbox is located on the building's ground floor, in the room next to the freight elevators (also accessible directly from the loading dock on Vining Street).

      Samples will be picked up every Wednesday at 3:00 PM.

      Courier service for this new dropbox will officially start on Wednesday, February 22, 2017. Please place your samples and a copy of your order form in the dropbox BEFORE 3:00 PM.

      Sincerely,

      The MGH CCIB DNA Core Team

      ________________________________________________

      MGH CCIB DNA Core Facility Closed for Presidents' Day (February 20, 2017)

      Posted on February 15, 2017

      Dear Core Users,

      In observance of Presidents' Day, the DNA Core Facility will be closed on Monday, February 20, 2017. Our Courier service will not be operating on this day, and samples will not be picked up from or delivered to our remote drop box locations.
      Our on-site drop box at 38 Sidney Street (Cambridge, MA) will be accessible on this day. Please note that samples will be kept at ambient temperature until Tuesday morning, February 21.

      If you should need any help planning your orders with us, please don't hesitate to contact us.

      Sincerely,

      The Core Staff

      ________________________________________________

      Winter Storm Closing

      Posted on February 9, 2017

      Due to the inclement weather, our core facility is closed today for the safety of our staff. Orders will not be processed, and samples will not be picked up from our remote dropboxes today.

      We will resume our normal business hours tomorrow, Friday, February 10, at 8 am.

      Stay safe and warm.

      - The MGH CCIB DNA Core Team

      ________________________________________________

      Holiday Closure Announcement

      Posted on December 14, 2016

      Dear Core Users,

      Our facility will be closed on Monday, December 26 and on Monday, January 2, 2017 due to Christmas and New Year's holidays. On both days, our courier service will not be operating, and our on-site dropbox will be only accessible with a key card as the entrance to the building will be locked.

      The entire CCIB DNA Core team wishes you a safe and happy holiday season. We would also like to take this opportunity to thank you for your business this year. It has been a pleasure helping you reach your goals, and we look forward to contributing to your success in 2017.

      ________________________________________________

      USER ALERT!

      Scheduled Server Maintenance: Permanent Deletion of Old Data Files on Sunday, January 1, 2017

      Posted on November 28, 2016

      Dear Users,

      On Sunday, January 1, 2017, we will permanently remove all old sequencing data files from our server. We strongly encourage you to download all of your data that were generated at our core facility before January 1, 2016.

      Please accept our apologies for the inconvenience.

      ~ The CCIB DNA Core Team

      ________________________________________________


      Effective October 1, 2016: FY17 Service Fees

      Posted on September 19, 2016

      Dear Core Users:

      Our FY'17 service fee structure has now been set after discussion with Partners Research Finance Management and goes into effect as of October 1, 2016. The new service fees reflect small increases in the costs of reagents, consumables and labor, and these fees support both our continuous process improvement efforts and the implementation of additional and/or improved service features, in particular for our high-demand Next-Gen Sequencing applications. Although we would like to keep our current rates, these increases were mandated by Partners policies that dictate that Cores recover their operating costs while not generating revenues in excess of their operating costs. Please be assured that we have done our best to hold down costs for you but we do not want to compromise on quality. Our new rates guarantee that we can continue to provide the same level of quality and service that you have come to expect from us.

      All orders that started being processed this month but are completed on or after October 1, 2016, will be invoiced at current (FY'16) pricing. Orders that are placed close to the end of September but are not processed before October 1, 2016, will be invoiced according to our new FY'17 pricing structure.

      We appreciate your past patronage and look forward to serving your future research needs.

      ~ The CCIB DNA Core Team

      ________________________________________________


      Thanksgiving Holiday Schedule

      Posted on November 17, 2016

      Dear Core Users,

      The CCIB DNA Core will be closed November 24 and November 25, 2016. Our Courier Service is not operating on either day, and samples will not be picked up from any of our remote dropbox locations. Direct sample drop-off at 38 Sidney Street is also not available on both days since the entrance to the main building (The Clark Building) will be locked on both days. The core facility will resume its regular business hours on November 28, 2016.

      Please note that you might experience 2 to 3 business days of delay in the processing of your order(s) due to the holiday break. We are working very hard to reduce this delay as much as possible - but we simply believe that our dedicated core team deserves the opportunity to spend Thanksgiving with their families. If you have specific questions about your order or are concerned about the availability of your data, please contact us at dnacore@ccib.mgh.harvard.edu.

      Thank you for being our valued customers. We are grateful for the pleasure of serving you and meeting your research needs.

      We wish you a lovely Thanksgiving and a joyous holiday season.

      Nicole Stange-Thomann, Ph.D.
      Director, CCIB DNA Core

      ________________________________________________


      CCIB DNA Core Facility Closed for Columbus Day
      (October 10, 2016)

      Posted on October 5, 2016

      Dear Core Users,

      In observance of Columbus Day, the DNA Core Facility will be closed on Monday, October 10, 2016. Our Courier service will not be operating on this day, and samples will not be picked up from or delivered to our remote dropbox locations. Our on-site dropbox will be accessible on this day. Please note that samples will be kept at ambient temperature until Tuesday morning, October 11.

      If you should need any help planning your orders with us, please don't hesitate to contact us.

      Happy Columbus Day!

      Sincerely,

      The CCIB DNA Core Staff

      ________________________________________________

      CCIB DNA Core Facility Closed for Labor Day
      (September 5, 2016)

      Posted on August 30, 2016

      Dear Core Users,

      In observance of Labor Day, the DNA Core Facility will be closed on Monday, September 5, 2016. Please note that our courier service will not be operating on this day; samples will not be picked up from our remote dropbox locations, and orders will not be delivered to any dropbox.
      Our on-site drop box will be only accessible with a key card as the entrance to the Clark Building (38 Sidney Street, Cambridge, MA) will be locked on this day.

      If you should need any assistance planning your orders with us, please don't hesitate to contact us.

      Wishing you a Happy Labor Day!

      The CCIB DNA Core Staff

      ________________________________________________


      Holiday Closure on Monday, July 4, 2016: Observance of Independence Day

      Posted on June 27, 2016

      The CCIB DNA Core Facility will be closed on Monday, July 4, 2016 in observance of Independence Day.

      Our Courier service will not be operating on this day, and samples will not be picked up from or delivered to our remote dropbox locations. Our onsite dropbox will be only accessible with a key card as the entrance to the Clark Building (Suite 100, 38 Sidney Street, Cambridge, MA) will be locked.

      Service turnaround times may be slightly longer as we expect larger order volumes due to the holiday. We are doing our best to process your orders as quickly as possible.

      If you should need any help planning your orders with us, please don't hesitate to contact us.

      Wishing you a happy, safe 4th of July!

      ~ The Core Team

      ________________________________________________



      CCIB DNA Core Facility Closed for Memorial Day
      (May 30, 2016)

      Posted on May 23, 2016

      Dear Core Users,

      In observance of Memorial Day, the DNA Core Facility will be closed on Monday, May 30, 2016. Our Courier service will not be operating on this day, and samples will not be picked up from or delivered to our remote drop box locations. Our on-site drop box will be only accessible with a key card as the entrance to the Clark Building (38 Sidney Street, Cambridge, MA) will be locked.

      If you should need any help planning your orders with us, please don't hesitate to contact us.

      We hope you'll enjoy the Memorial Day Weekend!

      Sincerely,

      The CCIB DNA Core Team

      ________________________________________________



      Contact Us   We want to hear from you!

         Posted on May 13, 2016


      We need your feedback to assess the demand for a sample dropbox in the Longwood Medical and Academic area.

      If your lab is in the Longwood area, please take a few minutes out of your busy schedule and tell us, which of our services you are using (or are planning to use in the near future), and on how many days per week you would need our sample pick-up service.

      Thank you!

      ~ The CCIB DNA Core Team

      ________________________________________________

      Meet Us

      BWH Research Cores Fair: Monday, April 25, 2016, 12-2 PM

      Meet us and learn more about our core and our research services!
      We are looking forward to seeing you at our table from 12-2 PM in Carrie Hall!

      Posted on April 20, 2016

      ________________________________________________

      Updated: List of Core-contributed PublicationsThanks

      Posted on March 3, 2016

      We'd like to express our gratitude to all of our users who are formally acknowledging the contributions of the CCIB DNA Core in their publications!

      Please check out our updated publication list here.

      ________________________________________________

      Winter Storm Causes Slight Turnaround Time Delay

      Posted on February 8, 2016

      Due to inclement weather, a slight delay in processing your order can be expected. Your patience is greatly appreciated.

      Turnaround times will go back to normal core operations tomorrow, Tuesday, February 9, 2016.

      Sincerely,
      The CCIB DNA Core Team

      ________________________________________________

      USER ALERT!


      Scheduled Server Maintenance: Permanent Deletion of Old Data Files on Monday, February 1, 2016

      Posted: January 8, 2016

      Dear Users,

      On Monday, February 1, 2016, we will permanently remove all old sequencing data files from our server. We strongly encourage you to download all of your data that were generated at our core facility before January 1, 2015.

      Please accept our apologies for the inconvenience.

      ~ The CCIB DNA Core Team

      ________________________________________________




      Connect With Us on Facebook and Twitter

      Posted on December 23, 2015

      Like us. Follow us. Tweet us. Join us.

      There's a whole lot more to learn about us. You now have a new way online to connect with the CCIB DNA Core and stay abreast of our latest news. Simply click on the social media buttons at the top of our webpage (right below our webpage banner), and you will be automatically directed to our new networking sites.

      On our Facebook page, you'll find postings about our services, special events and updates, important announcements, lots of pictures and short videos of our lab processes and our various automated platforms in action, and much more. Plus, you can follow our news, announcements, and service updates and highlights via Twitter.

      So, Like us and Follow us today!

      New Sample Dropbox at the Ragon Institute!NEW

      Posted on November 9, 2015

      We are pleased to announce the establishment of a new sample dropbox location in the lobby (1st floor) of the Ragon Institute of MGH, MIT and Harvard. Free pickup service will be provided Mondays through Fridays (with the exception of official MGH Holidays).

      Courier service for this new dropbox will officially start on Wednesday, November 11, 2015. Please place your samples and a copy of your order form in the dropbox no later than 11 AM.

      Sincerely,
      The CCIB DNA Core Team

      ________________________________________________


      ________________________________________________

      Effective October 1, 2015: FY16 Service Fees

      Posted on September 23, 2015

      Dear Core Users:

      Our FY16 service fee structure has now been set after discussion with Partners Research Finance Management and will be effective October 1, 2015. The new service fees reflect the continuing increases in the costs of reagents, consumables and labor, and allow us to guarantee that the top-quality of our services will not be compromised in any way and to sustain our continued process improvements efforts. Although we would very much like to retain our current rates, these increases were mandated by Partners policies that dictate that Cores recover their operating costs while not generating revenues in excess of their operating costs.

      Thank you for your continuing patronage and support!

      ~ The CCIB DNA Core Team

      ________________________________________________

      USER ALERT!

      Scheduled Server Maintenance: Permanent Deletion of Old Data Files on Wednesday, April 15, 2015

      Posted on March 25, 2015

      Dear Users,

      On Wednesday, April 15, 2015, we will permanently remove all old sequencing data files from our server. We strongly encourage you to download all of your data that were generated at our core facility before January 1, 2014.

      Please accept our apologies for the inconvenience.

      ~ The CCIB DNA Core Team

      ________________________________________________



      NEW SERVICE ANNOUNCEMENT!

      CCIB DNA Core Introduces 2nd NGS-based Application: CRISPR SEQUENCING

      Posted on February 25, 2015

      We are pleased to announce the official launch of our new service - CRISPR Sequencing - a cost-effective, high-throughput strategy for identifying CRISPR/Cas-induced mutations using next-generation sequencing technology.

      Our new service is offered on a weekly basis, with its first official run taking off on Wednesday, March 4, 2015. If you would like to submit samples and haven't been part of our beta-testing phase, please
      contact us so we can activate your account.

      Please explore our website to learn more!

      ________________________________________________



      NEW on our Website: Convenient "ORDER NOW" Feature!

      Posted on February 9, 2015

      To make the order process easier and more efficient for our customers, we added a new ORDER NOW feature to our website. From now on you will see a new button called "ORDER NOW" which will be displayed on the top of our webpage. When you successfully logged into your account, just click this button and you will have the convenience of simply choosing the desired service from the menu. You will immediately be taken to the corresponding order form.

      We hope that you find this to be a convenient feature and look forward to your feedback.

      Enjoy.


      - The CCIB DNA Core Team

      ________________________________________________



      Service Schedule Change

      Complete Plasmid Sequencing - Now Offered Every Week

      Posted: January 7, 2015


      Due to the continuously increasing demand for our new and unique service, we are now offering a new service cycle every week. Turnaround time will be 8 to 9 business days (calculated from the submission deadline) but might vary slightly dependent on order volumes.

      For additional service details and important updates and announcements, please visit the respective service page here.

      ________________________________________________



      CCIB DNA Core Facility closed for Martin Luther King's Day (January 19, 2015)

      Posted on January 15, 2015

      Dear Core Customers:

      In observance of Martin Luther King's Birthday, the CCIB DNA Core Facility will be closed on Monday, January 19, 2015. Our Courier service will not be operating on this day, i.e. samples will not be picked up from or delivered to our remote dropbox locations. Our on-site dropbox at 38 Sidney Street (Cambridge, MA) will be accessible on this day. Please note that samples will be kept at R.T. until Tuesday morning, January 20.

      Please be advised to plan your experiments according to the relevant deadlines:

      • Sanger Sequencing / Fragment Analysis (Microsatellite/MLPA)

        Friday, 01-16-2015 - Samples received by 12:00 PM will be entering the production pipeline on the same day, and data will be posted on Tuesday, January 20, 2015.

      • Complete Plasmid Sequencing

        Data for samples submitted by January 7, 2015 should be available as early as Tuesday, January 20. Processing time for samples submitted in time for the January 14 deadline is not expected to increase.

      • DNA Synthesis

        Friday, 01-16-2015 - All oligonucleotide orders received before 5 PM will be outsourced to IDT. Dependent on IDT's shipping schedule, oligos will be delivered to our remote dropboxes on Tuesday, January 20 or on Wednesday, January 21.

      • Laboratory Automation

        Plasmid DNA Preparation: All orders received on Friday, January 16, 2015 will be processed on Tuesday, January 20.

        Mouse Genotyping: To ensure the standard weekly turnaround, orders have to be submitted and samples have to be received at the core laboratory no later than 1:00 PM on Tuesday, January 20. Results for all orders received on January 20 will be available on Friday, January 23.

      If you should need any help planning your orders with us, please don't hesitate to contact us.

      Sincerely,

      The CCIB DNA Core Staff

      ________________________________________________

      CCIB DNA Core Holiday Schedule

      Posted: December 23, 2014

      The CCIB DNA Core will be following a modified holiday schedule in observance of Christmas Day (December 25, 2014) and New Year's Day (January 1, 2015). Our normal schedule will resume on Friday, 01-02-2014. Please see below for details.

      • Sanger Sequencing / Fragment Analysis (Microsatellite/MLPA)

        Wednesday, 12-24-2014 - Samples received by 12:00 PM will enter the production pipeline on the same day, and data will be posted on Friday, December 26, 2014.

        Wednesday, 12-31-2014 - Samples received by 12:00 PM will be processed on the same day, and data will be posted on Friday, December 26, 2014.

      • Complete Plasmid Sequencing

        All samples submitted in time for the December 17 deadline are currently being processed. The corresponding NGS run followed by automated sequence assembly will be slightly delayed due to reduced staffing. As soon as the data becomes available, we will send out email notifications.

      • DNA Synthesis

        Wednesday, 12-24-2014 through Friday, 12-26-2014 - All oligonucleotide orders will be outsourced to IDT. Dependent on IDT's shipping schedule, oligos will be delivered to our remote dropboxes on Monday, December 29 or on Tuesday, December 30.

        Monday, 12-29-2014 - Our normal in-house DNA Synthesis will resume.

      • Mouse Genotyping

        Monday, 12-22-2014 - Results for all Mouse Genotyping orders received this Monday will be available on Wednesday, 12-24-2014.

        Monday, 12-29-2014 - Results for all Mouse Genotyping orders received on this day (before 1:00 PM) will be available on Wednesday, 12-31-2014.

      • 96-well Plasmid DNA Preparation

        Wednesday, 12-24-2014 - Dependent on the total number of service requests, orders might not be processed before Friday, 12-26-2014.

        Wednesday, 12-31-2014 - Dependent on the total number of service requests, orders might not be processed before Friday, 01-02-2014.

      We thank you for your loyalty and patronage throughout this year, and we look forward to continue supporting your research needs in 2015.

      Wishing you a wonderful Holiday Season and a happy, healthy, and successful New Year!

      The CCIB DNA Core

      ________________________________________________


      MGH Research Core Day

      Monday, December 22, 2014
      1:00 - 3:00 PM

      Simches 3rd Floor Conference Area

      ________________________________________________

      Dear Customers,

      Please stop by our table to learn what the CCIB DNA
      Core has to offer and speak with us about
      our brand-new services.

      Light refreshments will be provided, along with a raffle!

      We hope to see you all on Monday, December 22, 2014!

      ~ The CCIB DNA Core Team ~

      ________________________________________________


      NEW SERVICE ANNOUNCEMENT

      Complete Plasmid Sequencing - a unique NGS application

      Posted: September 4, 2014

      The CCIB DNA Core is excited to announce the official launch of its first and unique NGS-based service application.

      Our new Complete Plasmid Sequencing service combines massively parallel sequencing with automated sequence assembly and offers many advantages over conventional Primer Walking services, including high sequencing coverage, attractive pricing and faster turnaround.

      For additional service details and important updates and announcements, please visit the respective service page here.

      ________________________________________________

      CCIB DNA Core Facility closed for Labor Day (September 1, 2014)

      Posted: August 27, 2014

      Dear Core Customers,

      In observance of Labor Day, the DNA Core Facility will be closed on Monday, September 1, 2014. Our Courier service will not be operating on this day, i.e. samples will not be picked up from or delivered to our remote drop-box locations. Our on-site drop-box will also not be accessible as the entrance to the building will be locked.

      Please be advised to plan your experiments/orders according to the relevant deadlines:

      • Sequencing data for samples submitted in time for courier pick-up on Friday, August 29, will be available on Tuesday, September 2.

      • Oligonucleotide synthesis orders received on Friday, August 29 (before 5 pm!) will be delivered and/or available for pick-up on Tuesday, September 2. All orders placed between August 30 and September 1 will be ready on Wednesday, September 3.

      • 96-well Plasmid DNA Preparation orders received on Friday, August 29, will be processed on the same day or - dependent on the respective order volumes - on Tuesday, September 2. These orders will be entering the DNA sequencing pipeline and/or will be delivered to the corresponding drop-box location(s) on Tuesday, September 2 or on Wednesday, September 3.

      • To ensure the standard weekly turnaround of our Mouse Genotyping services, orders should be submitted by Tuesday, September 2 and must be received by our core facility before 1 pm. Results for all orders received on September 2 will be available on Friday, September 5.

      If you should need any help planning your orders with us, please don't hesitate to contact us.

      Happy Labor Day!

      The CCIB DNA Core Staff

      ________________________________________________

      WELCOME to our NEW WEBSITE !

      Posted: July 8, 2014

      The CCIB DNA Core is excited to announce the launch of its newly designed and improved website, which goes live today, Tuesday 8th July 2014 and is located at this URL address: https://ccibtest0.mgh.harvard.edu:8443/new-cgi-bin/.

      Our goal for the new website is to improve user friendliness, usability and appeal and to provide our current and prospective customers with an easier way to learn about our service portfolio with most accurate information. The new segmentation of the entrance to our service portfolio allows visitors to enter either via the service category or via a specific service of interest. Our clients can access information easily and on their own choice rather than sift through everything to decide and/or to find what is of interest to them. The addition of a search functionality to the new site allows to search the website content. The website will be updated on a regular basis, with news, service launches and new content.

      For the next couple of weeks, you will be able to toggle between the new and the old site. Once the old site retires, you will be automatically redirected to the new URL.

      If you should experience any problems viewing the new website with your PC or MAC or notice that any links are not working, please do get in touch to let us know.

      If you have any questions, comments or suggestions, please contact us via email or leave us your thoughts in our feedback form. We would really welcome your comments both positive and negative.

      We hope you will enjoy our new site, finding more service options and information each time!

      The CCIB DNA Core Team

      ________________________________________________

      On-site Oligonucleotide Pick-Up Station Moves to 65 Landsdowne Street

      Posted: May 9, 2014

      Dear Users of our DNA Synthesis Services,

      As of Monday, May 12, 2014, our current onsite pick-up station (38 Sidney Street, Cambridge, MA) will be moved to the Partners Research Building (65 Landsdowne Street, Cambridge, MA). This new pick-up station will be located behind the security desk in the lobby (1st floor) to provide convenient and easy access to your oligonucleotide orders.

      As usual, orders will be available for personal pick-up at this new location around 4 pm. Our onsite pick-up location will be discontinued.

      Sincerely,
      The CCIB DNA Core Team

      ________________________________________________


      Partners in Excellence Award for a CCIB DNA Core Staff Professional!

      Posted on March 21, 2014

      We are proud to announce that John Darga, Manager of our Laboratory Automation group, was nominated for and selected to receive an Individual 2013 Partners in Excellence award in the area of teamwork.

      John will be recognized at the MGH award celebration on Thursday, April 24, 2014, at 2.00 pm in the Bullfinch patio tents.

      ________________________________________________


      Now Available: Additional Sequencing Sample Dropbox in Lobby of Simches Building!

      Posted on January 14, 2014


      Dear CCIB DNA Core Users,

      We are pleased to announce that we have established an additional dropbox location for your sequencing samples. The new dropbox is conveniently located in the lobby (1st floor) of the Simches Building, in front of the glass wall on the left side of the entrance. Also for this new dropbox location, free pickup service is available Mondays through Fridays (with the exception of official MGH Holidays). Samples will be picked up at 10 am and delivered to our Core Facility in time for the day's queue. Please place your samples and a copy of your order form in the dropbox before the cut-off time.

      Please note that we will also continue to service our original dropbox on the 7th floor of the Simches Building.

      Sincerely,
      The CCIB DNA Core Team

      ________________________________________________


      Effective November 4, 2013: Automated Email Notification and Delivery of OD Files (96-Well Plasmid Preparation Service)

      Posted on November 4, 2013

      Dear DNA Core Customers,

      Effective immediately, the CCIB DNA Core Facility will send out automated emails to its customers to inform when 96-well Plasmid DNA Preparation Orders are completed and ready to be shipped back via Courier Service (shipment option currently for internal customers only). The file(s) with the corresponding quantitation data (OD260, OD280, 260/280, DNA concentration) will be included as an attachment.

      Sincerely,

      The CCIB DNA Core Staff

      ________________________________________________

      Effective October 1, 2013: FY14 Service Fees

      Posted on September 24, 2013

      Dear Clients:

      We would like to update you on our FY14 service fee structure, which has now been set after discussion with Partners Research Finance Management and will be effective October 1, 2013. The new service fees, which entail increases in some service costs, reflect modest increases in the associated reagent and labor costs. We are pleased to announce that the fees for our Oligonucleotide Synthesis and Mouse Genotyping services remain the same as in the previous fiscal year. Wherever fees have been increased, these increases were mandated by Partners policies that dictate that Cores recover their operating costs while not generating revenues in excess of their operating costs.

      Throughout the previous fiscal year, the Core has strongly engaged in continuous process improvement efforts to further increase the value of existing services and to rollout new Custom Molecular Biology & Sequencing services. Also in the new fiscal year, the Core will stay committed to evaluating and developing new services in order to meet the changing research needs of the Partners research community.

      Thank you for your patronage!!!

      Sincerely,

      The CCIB Team

      ________________________________________________

      Effective June 30, 2013: Online Access to Oligonucleotide Specification Info

      Posted on June 30 2013

      Dear DNA Core Customers,

      We are pleased to announce that effective immediately the CCIB DNA Core Facility will provide online access to oligonucleotide specifications for all DNA synthesis orders. Once orders are complete, a link will appear on the DNA synthesis order status page allowing users to download the specifications including sequence, molecular weight, yield, molarity, etc.

      Sincerely,
      The CCIB DNA Core Staff

      ________________________________________________

      Effective May 10, 2013: Launch of Long-Read DNA Sequencing Service

      Posted on April 25, 2013

      Dear DNA Core Customers,

      We are pleased to announce that effective immediately the DNA Core Facility will be providing a Long-Read DNA Sequencing Service as part of its Custom Molecular Biology & Sequencing Service portfolio. Compared to our standard sequencing protocol (typical Q20 read length > 700 bases), this new service delivers an additional 200 bases on average and can yield up to 1000 Q20 bases per sample. At this point in time, a minimum of 12 samples has to be submitted to take advantage of this service. Turnaround is between 24 and 48 hours. Please note that the rates for the new long-read service (detailshere) differ from those of our standard sequencing services and reflect slightly increased costs due to the implementation of a separate workflow, increased instrument time, and processing of partially filled plates.

      Sample Submission for Long-Read Sequencing:

      Please select the Long Read Sequencing option from the order menu under the Sequencing tab of our website and complete the submission sheet using the same guidelines that are in place for standard read sequencing orders.

      Looking very much forward to process your orders!

      Sincerely,
      The CCIB DNA Core

      Effective February 1, 2013: Revised Sequencing Workflow

      Posted on January 15, 2013

      Dear MGH DNA Core Client:

      In the context of our continuous process improvement efforts, we are implementing a revised sequencing workflow on February 1, 2013. As a result of this process change,sequencing ordersas well asplasmid preparations for sequencingcan contain amaximum of 95 samples per plate. Effective February 1, 2013, well positionH12must be left empty for all plate orders. Full plate submissions of 95 samples will still be charged at the current rates. Thank you for helping us to serve you even better!

      The MGH DNA Core

      ________________________________________________

      MGH Holiday Hours: Martin Luther King Jr.

      Posted on January 15, 2013

      The MGH DNA Core Facility will be closed Monday, January 21, 2013 in honor of Martin Luther King Jr.

      ________________________________________________

      Effective February 1, 2013: Revised Sequencing Workflow

      Posted on January 14, 2013

      In the context of our continuous process improvement efforts, we are implementing a revised sequencing workflow on February 1, 2013. As a result of this process change, sequencing orders as well as plasmid preparations for sequencing can contain a maximum of 95 samples per plate. Effective February 1, 2013, well position H12 must be left empty for all plate orders. Full plate submissions of 95 samples will still be charged at the current rates. Thank you for helping us to serve you even better!

      ________________________________________________

      Update on FY13 Service Fees and New Services

      Posted on December 18, 2012

      We would like to inform you about our new and enhanced services we have begun to offer and our FY13 service fee structure, which has now been set after discussion with Partners Research Finance Management and will be effective January 1, 2013. These fees, which entail increases in some service costs, reflect modest increases in some reagent and labor costs. We are pleased to announce that the fees for our bulk sequencing, bulk microsatellite analysis and 96-well plasmid preparation services remain the same as in the previous fiscal year. Wherever fees have been increased, these increases were mandated by Partners policies that dictate that Cores recover their operating costs while not generating revenues in excess of their operating costs.

      As a result of the Core's continuous process improvement efforts and its commitment to constantly evaluate and develop new services in order to meet the changing research needs of the Partners research community in a timely manner, we are pleased to announce the launch of our new Custom Molecular Biology and Sequencing Services that include our previous Plasmid Verification and Primer Walking Services, midi- and maxi-scale plasmid DNA preparations as well as special sequencing protocols. A detailed description of our new custom service portfolio will be provided on our new and improved website which we are planning to launch in February 2013. Until then, please contact Dr. Nicole Stange-Thomann, Core Director, directly for more information (email nstange-thomann@ccib.mgh.harvard.edu).

      In January 2013, we will also send out a survey to kindly ask for your valuable feedback on the DNA Core's overall performance as well as the quality of its individual services and your suggestions for further improvements and additional new services.

      The MGH DNA Core is committed to providing timely help to investigators in solving critical and diverse biological/biomedical questions by providing a portfolio of state-of-the-art molecular biology and genomics services, specialized expertise, detailed advice and individual support. We are looking forward to support your research needs through FY13 and beyond.

      Thank you for choosing the MGH DNA Core as your research partner!

      ________________________________________________