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Core-Contributed Publications

 

We appreciate acknowledgement in and notification of publications that involved the use of the MGH CCIB DNA Core. This helps us to demonstrate our value and enables us to obtain financial and other support so that we can continue to provide essential research services in the best ways possible. User publications acknowledging the contributions of the MGH CCIB DNA Core are listed below. We are updating this list periodically. Please let us know when your research is published or a grant is awarded.

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Congratulations to the following authors for their recent publications featuring data generated in the MGH CCIB DNA Core Facility:

2024

  • Armani-Tourret M, Gao C, Hartana CA, Sun W, Carrere L, Vela L, Hochroth A, Bellefroid M, Sbrolla A, Shea K: Selection of epigenetically privileged HIV-1 proviruses during treatment with panobinostat and interferon-σ2a. Cell 2024

  • Cuadrado C, Breedlove C, van Santen E, Joiner KS, van Santen VL, Toro H: Protection Against Infectious Bronchitis Virus Vaccine Recombinants and Chicken-Selected Vaccine Subpopulations. Avian Diseases 2024

  • Devkota S, Zhou R, Nagarajan V, Maesako M, Do H, Noorani A, Overmeyer C, Bhattarai S, Douglas JT, Saraf A: Familial Alzheimer mutations stabilize synaptotoxic γ-secretase-substrate complexes. Cell Reports 2024, 43

  • Dubey S, Chen Z, Jiang YJ, Talis A, Molotkov A, Ali A, Mintz A, Momen-Heravi F: Small extracellular vesicles (sEVs)-based gene delivery platform for cell-specific CRISPR/Cas9 genome editing. Theranostics 2024, 14:2777; [Free Article]

  • Hop PJ, Lai D, Keagle PJ, Baron DM, Kenna BJ, Kooyman M, Shankaracharya, Halter C, Straniero L, Asselta R: Systematic rare variant analyses identify RAB32 as a susceptibility gene for familial Parkinson's disease. Nature Genetics 2024:1-6

  • Kazemian N, Zhou T, Chalasani N, Narayan A, Cedeño Laurent JG, Alvarez HAO, Pakpour S: Long-Term Impact of Childhood Adversity on the Gut Microbiome of Nursing Students. International Journal of Environmental Research and Public Health 2024, 21:68; [Free Article]

  • Khoa LTP, Yang W, Shan M, Zhang L, Mao F, Zhou B, Li Q, Malcore R, Harris C, Zhao L: Quiescence enables unrestricted cell fate in naive embryonic stem cells. Nature Communications 2024, 15:1721; [Free Article]

  • McLean ZL, Gao D, Correia K, Roy JC, Shibata S, Farnum IN, Valdepenas-Mellor Z, Kovalenko M, Rapuru M, Morini E: Splice modulators target PMS1 to reduce somatic expansion of the Huntington's disease-associated CAG repeat. Nature Communications 2024, 15:3182; [Free Article]

  • Mueller J, Schimmer RR, Koch C, Schneiter F, Fullin J, Lysenko V, Pellegrino C, Klemm N, Russkamp N, Myburgh R: Targeting the mevalonate or Wnt pathways to overcome CAR T-cell resistance in TP53-mutant AML cells. EMBO Molecular Medicine 2024:1-30

  • Muñoz-Alía MÁ, Nace RA, Balakrishnan B, Zhang L, Packiriswamy N, Singh G, Warang P, Mena I, Narjari R, Vandergaast R: Surface-modified measles vaccines encoding oligomeric, prefusion-stabilized SARS-CoV-2 spike glycoproteins boost neutralizing antibody responses to Omicron and historical variants, independent of measles seropositivity. Mbio 2024:e02928-02923

  • Rosenthal ZC, Fass DM, Payne NC, She A, Patnaik D, Hennig KM, Tesla R, Werthmann GC, Guhl C, Reis SA: Epigenetic modulation through BET bromodomain inhibitors as a novel therapeutic strategy for progranulin-deficient frontotemporal dementia. Scientific Reports 2024, 14:9064; [Free Article]

  • Salvador-Garcia D, Jin L, Hensley A, Gȯlcük M, Gallaud E, Chaaban S, Port F, Vagnoni A, Planelles-Herrero VJ, McClintock MA: A force-sensitive mutation reveals a non-canonical role for dynein in anaphase progression. Journal of Cell Biology 2024, 223

2023

  • Chiaramida A, Obwar SG, Nordstrom AE, Ericsson M, Saldanha A, Ivanova EV, Griffin GK, Khan DH, Belizaire R: Sensitivity to targeted UBA1 inhibition in a myeloid cell line model of VEXAS syndrome. Blood Advances 2023

  • Choi J, Pakbaz S, Yepes LM, Cieniewicz EJ, Schmitt-Keichinger C, Labarile R, Minutillo SA, Heck M, Hua J, Fuchs M: Grapevine fanleaf virus RNA1-encoded proteins 1A and 1BHel suppress RNA silencing. Molecular Plant-Microbe Interactions 2023

  • Diamond A, Diaz-Garza AM, Li J, Slattery SS, Merindol N, Fantino E, Meddeb-Mouelhi F, Karas BJ, Barnabé S, Desgagné-Penix I: Instability of extrachromosomal DNA transformed into the diatom Phaeodactylum tricornutum. Algal Research 2023:102998

  • Etemad B, Sun X, Li Y, Melberg M, Moisi D, Gottlieb R, Ahmed H, Aga E, Bosch RJ, Acosta EP: HIV post-treatment controllers have distinct immunological and virological features. Proceedings of the National Academy of Sciences 2023, 120:e2218960120

  • Fricke R, Swenson CV, Roe LT, Hamlish NX, Shah B, Zhang Z, Ficaretta E, Ad O, Smaga S, Gee CL: Expanding the substrate scope of pyrrolysyl-transfer RNA synthetase enzymes to include non-σ-amino acids in vitro and in vivo. Nature Chemistry 2023:1-12

  • Fantino E, Awwad F, Merindol N, Garza AMD, Gélinas S-E, Robles GCG, Custeau A, Meddeb-Mouelhi F, Desgagné-Penix I: Bioengineering Phaeodactylum tricornutum, a marine diatom, for cannabinoid biosynthesis. Algal Research 2023:103379

  • Hartana CA, Garcia Broncano P, Maswabi K, Ajibola G, Moyo S, Mohammed T, Maphorisa C, Makhema J, Powis KM, Lockman S: Immune modulation of HIV-1 reservoir size in early-treated neonates. The Journal of Infectious Diseases 2023:jiad173

  • Kuehnle N, Osborne SM, Liang Z, Manzano M, Gottwein E: CRISPR screens identify novel regulators of cFLIP dependency and ligand-independent, TRAIL-R1-mediated cell death. Cell Death & Differentiation 2023:1-14

  • LaFleur MW, Lemmen AM, Streeter IS, Nguyen TH, Milling LE, Derosia NM, Hoffman ZM, Gillis JE, Tjokrosurjo Q, Markson SC: X-CHIME enables combinatorial, inducible, lineage-specific and sequential knockout of genes in the immune system. Nature Immunology 2023:1-11

  • Li Y-D, Ma MW, Hassan MM, Hunkeler M, Teng M, Puvar K, Lumpkin R, Sandoval B, Jin CY, Ficarro SB: Template-assisted covalent modification of DCAF16 underlies activity of BRD4 molecular glue degraders. bioRxiv 2023:2023.2002. 2014.528208

  • Lian X, Seiger KW, Parsons EM, Gao C, Sun W, Gladkov GT, Roseto IC, Einkauf KB, Osborn MR, Chevalier JM: Progressive transformation of the HIV-1 reservoir cell profile over two decades of antiviral therapy. Cell Host & Microbe 2023

  • Maalouf KE, Vaine CA, Frederick DM, Yoshinaga A, Obuchi W, Mahjoum S, Nieland L, Al Ali J, Bragg DC, Breakefield XO: Tracking human neurologic disease status in mouse brain/plasma using reporter-tagged, EV-associated biomarkers. Molecular Therapy 2023

  • Mojica-Perez SP, Stokes K, Jaklic DC, Jahagirdar S, Uhler M, Parent JM, Niu W: Protocol for selecting single human pluripotent stem cells using a modified micropipetter. STAR protocols 2023, 4:102629; [Free Article]

  • Nguyen VP, Song J, Prieskorn D, Zou J, Li Y, Dolan D, Xu J, Zhang J, Jayasundera KT, Yang J: USH2A gene mutations in rabbits lead to progressive retinal degeneration and hearing loss. Translational Vision Science & Technology 2023, 12:26-26

  • Schneider HM, Lor VS, Zhang X, Saengwilai P, Hanlon MT, Klein SP, Davis JL, Borkar AN, Depew CL, Bennett MJ: Transcription factor bHLH121 regulates root cortical aerenchyma formation in maize. Proceedings of the National Academy of Sciences 2023, 120:e2219668120

  • Sun Y, Revach O-y, Anderson S, Kessler EA, Wolfe CH, Jenney A, Mills CE, Robitschek EJ, Davis TG, Kim S: Targeting TBK1 to overcome resistance to cancer immunotherapy. Nature 2023:1-3

  • Tao Y, Lamas V, Du W, Zhu W, Li Y, Whittaker MN, Zuris JA, Thompson DB, Rameshbabu AP, Shu Y: Treatment of monogenic and digenic dominant genetic hearing loss by CRISPR-Cas9 ribonucleoprotein delivery in vivo. Nature Communications 2023, 14:4928

  • Terra MT, Macklin KS, Burleson M, Jeon A, Beckmann JF, Hauck R: Mapping the poultry insectome in and around broiler breeder pullet farms identifies new potential Dipteran vectors of Histomonas meleagridis. Parasites & Vectors 2023, 16:1-13

  • Tricoli DM, Debernardi JM: An Efficient Protoplast-based Genome Editing protocol for Vitis species. Horticulture Research 2023:uhad266

  • Ustinova K, Ruhnow F, Gili M, Surrey T: Microtubule binding of the human augmin complex is directly controlled by importins and Ran-GTP. Journal of Cell Science 2023, 136

  • Xu W, Plummer L, Seminara SB, Balasubramanian R, Lippincott MF: How human genetic context can inform pathogenicity classification: FGFR1 variation in idiopathic hypogonadotropic hypogonadism. Human Genetics 2023:1-9

  • Yu Y, Schneider WM, Kass MA, Michailidis E, Acevedo A, Pamplona Mosimann AL, Bordignon J, Koenig A, Livingston CM, van Gijzel H: An RNA-based system to study hepatitis B virus replication and evaluate antivirals. Science Advances 2023, 9:eadg6265

  • Zhang T, Alonzo I, Stubben C, Geng Y, Herdman C, Chandler N, Doane KP, Pluimer BR, Trauger SA, Peterson RT: A zebrafish model of Combined Saposin Deficiency identifies acid sphingomyelinase as a potential therapeutic target. Disease Models & Mechanisms 2023:dmm. 049995

2022

  • Arnold PK, Jackson BT, Paras KI, Brunner JS, Hart ML, Newsom OJ, Alibeckoff SP, Endress J, Drill E, Sullivan LB: A non-canonical tricarboxylic acid cycle underlies cellular identity. Nature 2022:1-5

  • Bloemeke N, Meighen-Berger K, Hitzenberger M, Bach NC, Parr M, Coelho JP, Frishman D, Zacharias M, Sieber SA, Feige MJ: Intra-membrane client recognition potentiates the chaperone functions of Calnexin. bioRxiv 2022

  • Brimble MA, Cheng P-H, Winston SM, Reeves IL, Souquette A, Spence Y, Zhou J, Wang Y-D, Morton CL, Valentine M: Preventing packaging of translatable P5-associated DNA contaminants in recombinant AAV vector preps. Molecular Therapy-Methods & Clinical Development 2022

  • Chu Z, Gu L, Hu Y, Zhang X, Li M, Chen J, Teng D, Huang M, Shen C-H, Cai L: STAG2 regulates interferon signaling in melanoma via enhancer loop reprogramming. Nature Communications 2022, 13:1-11

  • d'Amico EA, Ud Din Ahmad M, Cmentowski V, Girbig M, M ller F, Wohlgemuth S, Brockmeyer A, Maffini S, Janning P, Vetter IR: Conformational transitions of the Spindly adaptor underlie its interaction with Dynein and Dynactin. Journal of Cell Biology 2022, 221:e202206131

  • Deng L, Mojica-Perez SP, Azaria RD, Schultz M, Parent JM, Niu W: Loss of POGZ alters neural differentiation of human embryonic stem cells. Molecular and Cellular Neuroscience 2022:103727

  • Einkauf KB, Osborn MR, Gao C, Sun W, Sun X, Lian X, Parsons EM, Gladkov GT, Seiger KW, Blackmer JE: Parallel analysis of transcription, integration, and sequence of single HIV-1 proviruses. Cell 2022

  • Fricke R, Swenson C, Roe LT, Hamlish N, Ad O, Smaga S, Gee CL, Schepartz A: Orthogonal synthetases for polyketide precursors. bioRxiv 2022

  • Hartana CA, Garcia-Broncano P, Rassadkina Y, Lian X, Jiang C, Einkauf KB, Maswabi K, Ajibola G, Moyo S, Mohammed T: Immune correlates of HIV-1 reservoir cell decline in early-treated infants. Cell Reports 2022, 40:111126; [Free Article]

  • Hiratsuka K, Miyoshi T, Kroll KT, Gupta NR, Valerius MT, Ferrante T, Yamashita M, Lewis JA, Morizane R: Organoid-on-a-chip model of human ARPKD reveals mechanosensing pathomechanisms for drug discovery. Science Advances 2022, 8:eabq0866

  • Hutcheson RL, Hayes M, Sugden B: Optimal LentiCRISPR-Based System for Sequential CRISPR/Cas9 Screens. ACS Synthetic Biology 2022

  • Kurimchak AM, Herrera-Mont vez C, Montserrat-Sangr S, Araiza-Olivera D, Hu J, Neumann-Domer R, Kuruvilla M, Bellacosa A, Testa JR, Jin J: The drug efflux pump MDR1 promotes intrinsic and acquired resistance to PROTACs in cancer cells. Science Signaling 2022, 15:eabn2707

  • Lainscek D, Forstneric V, Mikolic V, Malensek S, Pecan P, Bencina M, Sever M, Podgornik H, Jerala R: Coiled-coil heterodimer-based recruitment of an exonuclease to CRISPR/Cas for enhanced gene editing. Nature Communications 2022, 13:1-12

  • Moen JM, Mohler K, Rogulina S, Shi X, Shen H, Rinehart J: Enhanced access to the human phosphoproteome with genetically encoded phosphothreonine. Nature Communications 2022, 13:1-14

  • O'Brien K, Ughetto S, Mahjoum S, Nair AV, Breakefield XO: Uptake, functionality, and re-release of extracellular vesicle-encapsulated cargo. Cell Reports 2022, 39:110651

  • O'Geen H, Tomkova M, Combs JA, Tilley EK, Segal DJ: Determinants of heritable gene silencing for KRAB-dCas9+ DNMT3 and Ezh2-dCas9+ DNMT3 hit-and-run epigenome editing. Nucleic Acids Research 2022

  • Pasin F: Assembly of plant virus agroinfectious clones using biological material or DNA synthesis. STAR Protocols 2022, 3:101716; [Free Article]

  • Rajasekaran S, Khan E, Ching SR, Khan M, Siddiqui JK, Gradia DF, Lin C, Bouley SJ, Mercadante DL, Manning AL: PUMILIO competes with AUF1 to control DICER1 RNA levels and miRNA processing. Nucleic Acids Research 2022

  • Rufino-Ramos D, Lule S, Mahjoum S, Ughetto S, Bragg DC, de Almeida LP, Breakefield XO, Breyne K: Using genetically modified extracellular vesicles as a non-invasive strategy to evaluate brain-specific cargo. Biomaterials 2022:121366

  • Shin JW, Hong EP, Park SS, Choi DE, Seong IS, Whittaker MN, Kleinstiver BP, Chen RZ, Lee J-M: Allele-specific silencing of the gain-of-function mutation in Huntington's disease using CRISPR-Cas9. JCI insight 2022

  • Tinney KR, Dover JA, Doore SM, Parent KN: Shigella viruses Sf22 and KRT47 require outer membrane protein C for infection. Biochimica et Biophysica Acta (BBA)-Biomembranes 2022, 1864:183920

  • To C, Beyett TS, Jang J, Feng WW, Bahcall M, Haikala HM, Shin BH, Heppner DE, Rana JK, Leeper BA: Allosteric inhibition of drug resistant forms of EGFR L858R mutant NSCLC. Nature cancer 2022, 3:402; [Free Article]

  • Umeh-Garcia M, O'Geen H, Simion C, Gephart MH, Segal DJ, Sweeney CA: Aberrant promoter methylation contributes to LRIG1 silencing in basal/triple-negative breast cancer. British Journal of Cancer 2022:1-13

  • Wang J, Zhang Y, Mendonca CA, Yukselen O, Muneeruddin K, Ren L, Liang J, Zhou C, Xie J, Li J: AAV-delivered suppressor tRNA overcomes a nonsense mutation in mice. Nature 2022:1-6

  • Yang E, Huang S, Jami-Alahmadi Y, McInerney GM, Wohlschlegel JA, Li MM: Elucidation of TRIM25 ubiquitination targets involved in diverse cellular and antiviral processes. PLoS pathogens 2022, 18:e1010743; [Free Article]

2021

  • Coggins NB, O'Geen H, Lott PC, Segal DJ, Carmona LC: Scarless genome editing reveals risk SNP rs6983267-G and lncRNA CCAT2 dictate targetable PI3K signaling dependence in WNT-dysregulated CRC. 2021

  • De Luca T, Stratford RE, Edwards ME, Ferreira CR, Benson EA: Novel Quantification of Extracellular Vesicles with Unaltered Surface Membranes Using an Internalized Oligonucleotide Tracer and Applied Pharmacokinetic Multiple Compartment Modeling. Pharmaceutical Research 2021:1-19

  • Eser P , Paranal RM, Son J, Ivanova E, Kuang Y, Haikala HM, To C, Okoro JJ, Dholakia KH, Choi J: Oncogenic switch and single-agent MET inhibitor sensitivity in a subset of EGFR-mutant lung cancer. Science Translational Medicine 2021 [Free Article]

  • Feng X, Del Amo VL, Mameli E, Lee M, Bishop AL, Perrimon N, Gantz VM: Optimized CRISPR tools and site-directed transgenesis towards gene drive development in Culex quinquefasciatus mosquitoes. Nature Communications 2021, 12:1-13

  • Gener AR, Foley BT, Hyink DP, Klotman PE: Reference plasmid pHXB2_D is an HIV-1 molecular clone that exhibits identical LTRs and a single integration site indicative of an HIV provirus. bioRxiv 2021:611848

  • Harmon RM, Devany J, Gardel M: Dia1 Coordinates Differentiation and Cell Sorting in a Stratified Epithelium. bioRxiv 2021:2021.2001. 2004.425231

  • Houser MC, Turchyna Y, Perrin F, Chibnik L, Berezovska O, Maesako M: Limited Substrate Specificity of PS/y-Secretase Is Supported by Novel Multiplexed FRET Analysis in Live Cells. Biosensors 2021, 11:169;

  • Jung R, Lee Y, Barker D, Correia K, Shin B, Loupe J, Collins RL, Lucente D, Ruliera J, Gillis T: Mutations causing Lopes-Maciel-Rodan Syndrome are huntingtin hypomorphs. Human Molecular Genetics 2021

  • Lee GQ: Chemistry and Bioinformatics Considerations in Using Next-Generation Sequencing Technologies to Inferring HIV Proviral DNA Genome-Intactness. Viruses 2021, 13:1874;

  • Luu AP, Yao Z, Ramachandran S, Azzopardi SA, Miles LA, Schneider WM, Hoffmann H, Bozzacco L, Garcia G, Gong D: A CRISPR Activation Screen Identifies an Atypical Rho GTPase That Enhances Zika Viral Entry. Viruses 2021, 13:2113;

  • Muthuirulan P, Zhao D, Young M, Richard D, Liu Z, Emami A, Portilla G, Hosseinzadeh S, Cao J, Maridas D: Joint disease-specificity at the regulatory base-pair level. Nature Communications 2021, 12:1-16

  • O'Neill CE, Skilton RJ, Forster J, Cleary DW, Pearson SA, Lampe DJ, Thomson NR, Clarke IN: An inducible transposon mutagenesis approach for the intracellular human pathogen Chlamydia trachomatis. Wellcome Open Research 2021, 6:312

  • Shirasaki R, Matthews GM, Gandolfi S, de Matos Simoes R, Buckley DL, Vora JR, Sievers QL, Br ggenthies JB, Dashevsky O, Poarch H: Functional Genomics Identify Distinct and Overlapping Genes Mediating Resistance to Different Classes of Heterobifunctional Degraders of Oncoproteins. Cell Reports 2021, 34:108532; [Free Article]

  • Skilton RJ, O'Neill C, Thomson NR, Lampe DJ, Clarke IN: Progress towards an inducible, replication-proficient transposon delivery vector for Chlamydia trachomatis. Wellcome Open Research 2021, 6:82

  • Vandergaast R, Carey T, Reiter S, Lathrum C, Lech P, Gnanadurai C, Haselton M, Buehler J, Narjari R, Schnebeck L: IMMUNO-COV v2. 0: Development and Validation of a High-Throughput Clinical Assay for Measuring SARS-CoV-2-Neutralizing Antibody Titers. medRxiv 2021

  • Xue Y, Wang SK, Rana P, West ER, Hong CM, Feng H, Wu DM, Cepko CL: AAV-Txnip prolongs cone survival and vision in mouse models of retinitis pigmentosa. bioRxiv 2021

  • Yang Y, Wu W, Liu T, Dong L, Lei H: A robust method for protein depletion based on gene editing. Methods 2021

  • Yeung V, Sriram S, Tran JA, Guo X, Hutcheon AE, Zieske JD, Karamichos D, Ciolino JB: FAK Inhibition Attenuates Corneal Fibroblast Differentiation In Vitro. Biomolecules 2021, 11:1682;

  • Yokoyama R, de Oliveira MV, Kleven B, Maeda HA: The entry reaction of the plant shikimate pathway is subjected to highly complex metabolite-mediated regulation. The Plant Cell 2021

2020

  • Bosch JA, Colbeth R, Zirin J, Perrimon N: Gene knock-ins in Drosophila using homology-independent insertion of universal donor plasmids. Genetics 2020, 214:75-89; [Free Article]

  • Chatterjee P, Lee J, Nip L, Koseki SR, Tysinger E, Sontheimer EJ, Jacobson JM, Jakimo N: A Cas9 with PAM recognition for adenine dinucleotides. Nature Communications 2020

  • Cochrane RR, Brumwell SL, Shrestha A, Giguere DJ, Hamadache S, Gloor GB, Edgell DR, Karas BJ: Cloning of Thalassiosira pseudonana's Mitochondrial Genome in Saccharomyces cerevisiae and Escherichia coli. Biology 2020, 9:358

  • Cochrane RR, Brumwell SL, Soltysiak MP, Hamadache S, Davis JG, Wang J, Tholl SQ, Janakirama P, Edgell DR, Karas BJ: Rapid method for generating designer algal mitochondrial genomes. Algal Research 2020, 50:102014

  • Daer R, Hamna F, Barrett CM, Haynes KA: Site-directed targeting of transcriptional activation-associated proteins to repressed chromatin restores CRISPR activity. APL bioengineering 2020, 4:016102; [Free Article]

  • De Luca T, Stratford RE, Edwards ME, Ferreira CR, Benson EA: Quantification of extracellular vesicles with unaltered surface membranes using an internalized oligonucleotide tracer and droplet digital PCR applied to modeling of in vivo kinetics.bioRxiv 2020

  • Halmai JA, Deng P, Gonzalez CE, Coggins NB, Cameron D, Carter JL, Buchanan FK, Waldo JJ, Lock SR, Anderson JD: Artificial escape from XCI by DNA methylation editing of the CDKL5 gene. Nucleic Acids Research 2020

  • Hoffmann H-H, Schneider WM, Rozen-Gagnon K, Miles LA, Schuster F, Razooky B, Jacobson E, Wu X, Yi S, Rudin CM: TMEM41β is a pan-flavivirus host factor. bioRxiv 2020

  • House NC, Layer JV, Price BD: Site-specific targeting of a light activated dCas9-KIllerRed fusion protein generates transient, localized regions of oxidative DNA damage. bioRxiv 2020

  • Hsiao F, Frouard J, Gramatica A, Xie G, Telwatte S, Lee GQ, Roychoudhury P, Schwarzer R, Luo X, Yukl SA: Tissue memory CD4+ T cells expressing IL-7 receptor-alpha (CD127) preferentially support latent HIV-1 infection. PLoS pathogens 2020, 16:e1008450;

  • Jones SI, Hunt MR, Vodkin LO: An embryo lethal transgenic line manifests global expression changes and elevated protein/oil ratios in heterozygous soybean plants. PLOS ONE 2020, 15:e0233721; [Free Article]

  • Karaayvaz-Yildirim M, Silberman RE, Langenbucher A, Saladi SV, Ross KN, Zarcaro E, Desmond A, Yildirim M, Vivekanandan V, Ravichandran H: Aneuploidy and a deregulated DNA damage response suggest haploinsufficiency in breast tissues of BRCA2 mutation carriers. Science advances 2020, 6:eaay2611; [Free Article]

  • Kinloch NN, Ren Y, Alberto WDC, Dong W, Khadka P, Huang SH, Mota TM, Wilson A, Shahid A, Kirkby D: HIV Diversity Considerations in the Application of the Intact Proviral DNA Assay (IPDA). BioRxiv2020

  • Korecka JA, Thomas R, Hinrich AJ, Moskites AM, Macbain ZK, Hallett PJ, Isacson O, Hastings ML: Splice-switching antisense oligonucleotides reduce LRRK2 kinase activity in human LRRK2 transgenic mice.Molecular Therapy-Nucleic Acids 2020, 21:623-635; [Free Article]

  • Kuo H-H, Banga R, Lee GQ, Gao C, Cavassini M, Corpataux J-M, Blackmer JE, zur Wiesch S, Xu GY, Pantaleo G: Blood and Lymph Node Dissemination of Clonal Genome-Intact Human Immunodeficiency Virus 1 DNA Sequences During Suppressive Antiretroviral Therapy. The Journal of Infectious Diseases 2020, 20:1-6

  • Leibowitz ML, Papathanasiou S, Doerfler PA, Blaine LJ, Yao Y, Zhang C-Z, Weiss MJ, Pellman D: Chromothripsis as an on-target consequence of CRISPR-Cas9 genome editing. bioRxiv 2020

  • Lewy TG, Offerdahl DK, Grabowski JM, Kellman E, Mlera L, Chiramel A, Bloom ME: PERK-Mediated Unfolded Protein Response Signaling Restricts Replication of the Tick-Borne Flavivirus Langat Virus. Viruses 2020, 12:328

  • Liu P-T, Keele BF, Abbink P, Mercado NB, Liu J, Bondzie EA, Chandrashekar A, Borducchi EN, Hesselgesser J, Mish M: Origin of rebound virus in chronically SIV-infected Rhesus monkeys following treatment discontinuation. Nature Communications 2020, 11:1-9

  • Ma L, Ruan J, Song J, Wen L, Yang D, Zhao J, Xia X, Chen YE, Zhang J, Xu J: MiCas9 increases large size gene knock-in rates and reduces undesirable on-target and off-target indel edits. Nature Communications 2020, 11:1-11

  • Ng SR, Rideout WM, Akama-Garren EH, Bhutkar A, Mercer KL, Schenkel JM, Bronson RT, Jacks T: CRISPR-mediated modeling and functional validation of candidate tumor suppressor genes in small cell lung cancer. Proceedings of the National Academy of Sciences 2020, 117:513-521; [Free Article]

  • Nouemssi SB, Ghribi M, Beauchemin R, Meddeb-Mouelhi F, Germain H, Desgagn -Penix I: Rapid and Efficient Colony-PCR for High Throughput Screening of Genetically Transformed Chlamydomonas reinhardtii. Life 2020, 10:186

  • Ott CJ, Zhang T, Kwiatkowski NP, Laubach JP, Schlossman RL, Richardson PG, Culhane AC, Groen RW, Fischer ES, Vazquez F: Functional Genomics Identify Distinct and Overlapping Genes Mediating Resistance to Different Classes of Heterobifunctional Degraders of Oncoproteins. Cell Reports 2020

  • Pascolutti R, Erlandson SC, Burri DJ, Zheng S, Kruse AC: Mapping and engineering the interaction between adiponectin and T-cadherin. Journal of Biological Chemistry 2020:jbc. RA119. 010970

  • Reyes M, Kagami M, Kawashima S, Pallotta J, Schnabel D, Fukami M, J ppner H: A novel GNAS duplication associated with loss-of-methylation restricted to exon A/B causes pseudohypoparathyroidism type Ib (PHP1B). Journal of Bone and Mineral Research 2020

  • Somprasong N, Hall CM, Webb JR, Sahl JW, Wagner DM, Keim P, Currie BJ, Schweizer HP: Burkholderia ubonensis high-level tetracycline resistance is due to efflux pump synergy involving a novel TetA (64) resistance determinant. Antimicrobial Agents and Chemotherapy 2020

  • ten Hacken E, Clement K, Li S, Hern ndez-S nchez M, Redd R, Wang S, Ruff D, Gruber M, Baranowski K, Jacob J: High throughput single-cell detection of multiplex CRISPR-edited gene modifications. Genome Biology 2020, 21:1-11

  • Yang Y, Huang X, Ma G, Cui J, Matsubara JA, Kazlauskas A, Zhao J, Wang J, Lei H: PDGFRb plays an essential role in patient vitreous-stimulated contraction of retinal pigment epithelial cells from epiretinal membranes. Experimental Eye Research 2020:108116

  • Zabala G, Kour A, Vodkin LO: Overexpression of an ethylene-forming ACC oxidase (ACO) gene precedes the Minute Hilum seed coat phenotype in Glycine max. BMC Genomics 2020, 21:1-20

  • Zhao M, Garc a B, Gallo A, Tzanetakis IE, Sim n-Mateo C, Garc a JA, Pasin F: Home-made enzymatic premix and Illumina sequencing allow for one-step Gibson assembly and verification of virus infectious clones. Phytopathology Research 2020, 2:1-9

2019

  • Alapati D, Zacharias WJ, Hartman HA, Rossidis AC, Stratigis JD, Ahn NJ, Coons B, Zhou S, Li H, Singh K: In utero gene editing for monogenic lung disease. Science translational medicine 2019, 11:eaav8375; [Free Article]

  • Assetta B, Morris-Love J, Gee GV, Atkinson AL, O'Hara BA, Maginnis MS, Haley SA, Atwood WJ: Genetic and Functional Dissection of the Role of Individual 5-HT2 Receptors as Entry Receptors for JC Polyomavirus. Cell Reports 2019, 27:1960-1966. e1966; [Free Article]

  • Boone PG, Rochelle LK, Ginzel JD, Lubkov V, Roberts WL, Nicholls P, Bock C, Flowers ML, von Furstenberg RJ, Stripp BR: A cancer rainbow mouse for visualizing the functional genomics of oncogenic clonal expansion. Nature Communications 2019, 10:1-15

  • Coyne MJ, B chon N, Matano LM, McEneany VL, Chatzidaki-Livanis M, Comstock LE: A family of anti-Bacteroidales peptide toxins wide-spread in the human gut microbiota. Nature Communications 2019, 10:3460; [Free Article]

  • da Hora CC, Pinkham K, Carvalho L, Zinter M, Tabet E, Nakano I, Tannous BA, Badr CE: Sustained NF-kB-STAT3 signaling promotes resistance to Smac mimetics in Glioma stem-like cells but creates a vulnerability to EZH2 inhibition. Cell Death Discovery 2019, 5:72

  • Demircioglu E, Zheng W, McQuown AJ, Maier N, Watson N, Cheeseman IM, Denic V, Egelman EH, Schwartz TU: The AAA+ ATPase TorsinA polymerizes into hollow tubes with a helical periodicity of 8.5 subunits per turn. bioRxiv 2019:567099

  • Garc a-Bayona L, Comstock LE: Streamlined Genetic Manipulation of Diverse Bacteroides and Parabacteroides Isolates from the Human Gut Microbiota. mBio 2019, 10:e01762-01719; [Free Article]

  • Han H, Chen N, Huang X, Liu B, Tian J, Lei H: Phosphoinositide-3-kinase & inactivation prevents vitreous-induced activation of AKT/MDM2/p53 and migration of retinal pigment epithelial cells. Journal of Biological Chemistry 2019:jbc. RA119. 010130

  • Hinze L, Pfirrmann M, Karim S, Degar J, McGuckin C, Vinjamur D, Sacher J, Stevenson KE, Neuberg DS, Orellana E: Synthetic lethality of Wnt pathway activation and asparaginase in drug-resistant acute leukemias. Cancer Cell 2019, 35:664-676. e667; [Free Article]

  • Jamshidi F, Place EM, Mehrotra S, Navarro-Gomez D, Maher M, Branham KE, Valkanas E, Cherry TJ, Lek M, MacArthur D: Contribution of noncoding pathogenic variants to RPGRIP1-mediated inherited retinal degeneration. Genetics in Medicine 2019, 21:694-704; [Free Article]

  • Lee GQ, Reddy K, Einkauf KB, Gounder K, Chevalier JM, Dong KL, Walker BD, Xu GY, Ndung'u T, Lichterfeld M: HIV-1 DNA sequence diversity and evolution during acute subtype C infection. Nature Communications 2019, 10:2737; [Free Article]

  • Major KM, Weston DP, Lydy MJ, Huff Hartz KE, Wellborn GA, Manny AR, Poynton HC: The G119S ace-1 mutation confers adaptive organophosphate resistance in a nontarget amphipod. Evolutionary Applications 2019

  • McCully LM, Bitzer AS, Seaton SC, Smith LM, Silby MW: Interspecies Social Spreading: Interaction between Two Sessile Soil Bacteria Leads to Emergence of Surface Motility. mSphere 2019, 4:e00696-00618; [Free Article]

  • Merola J, Reschke M, Pierce RW, Qin L, Spindler S, Baltazar T, Manes TD, Lopez-Giraldez F, Li G, Bracaglia LG: Progenitor-derived human endothelial cells evade alloimmunity by CRISPR/Cas9-mediated complete ablation of MHC expression. JCI insight 2019

  • Ndegwa E, Almehmadi H, Kim C, Kaseloo P, Ako AA: Longitudinal Shedding Patterns and Characterization of Antibiotic Resistant E. coli in Pastured Goats using a Cohort Study. Antibiotics 2019, 8:136

  • O'Geen H, Bates SL, Carter SS, Nisson KA, Halmai J, Fink KD, Rhie SK, Farnham PJ, Segal DJ: Ezh2-dCas9 and KRAB-dCas9 enable engineering of epigenetic memory in a context-dependent manner. Epigenetics & Chromatin 2019, 12:26

  • Petrenko VA, Gillespie JW, Xu H, O'Dell T, De Plano LM: Combinatorial Avidity Selection of Mosaic Landscape Phages Targeted at Breast Cancer Cells-An Alternative Mechanism of Directed Molecular Evolution. Viruses 2019, 11:785

  • Schade AE, Oser MG, Nicholson HE, DeCaprio JA: Cyclin D-CDK4 relieves cooperative repression of proliferation and cell cycle gene expression by DREAM and RB. Oncogene 2019, 38:4962-4976; [Free Article]

  • Singh R, Perera SR, Katselis GS, Chumala P, Martin I, Kusalik A, Mitzel KM, Dillon J-AR: A β-lactamase-producing plasmid from Neisseria gonorrhoeae carrying a unique 6 bp deletion in bla TEM-1 encoding a truncated 24 kDa TEM-1 penicillinase that hydrolyses ampicillin slowly. Journal of Antimicrobial Chemotherapy 2019, 74:2904-2912;

  • Wan A, Place E, Pierce EA, Comander J: Characterizing variants of unknown significance in rhodopsin: a functional genomics approach. bioRxiv 2019:512897

  • Weston DP, Moschet C, Young TM: Chemical and Toxicological Effects on Cache Slough after Storm-Driven Contaminant Inputs. San Francisco Estuary and Watershed Science 2019, 17:3

  • Usmani SM, Murooka TT, Deruaz M, Koh WH, Sharaf RR, Di Pilato M, Power KA, Lopez P, Hnatiuk R, Vrbanac VD: HIV-1 balances the fitness costs and benefits of disrupting the host cell actin cytoskeleton early after mucosal transmission. Cell host & microbe 2019, 25:73-86. e75

  • Vinu L, Sater MR, Herriott I, Huntley MH, Jacoby GA, Hooper DC: Multiple copies of qnrA1 on an Inc A/C2 plasmid explain enhanced quinolone resistance in an Escherichia coli mutant. Antimicrobial Agents and Chemotherapy 2019:AAC. 00718-00719

2018

  • Breinig M, Schweitzer AY, Herianto AM, Revia S, Schaefer L, Wendler L, Galvez AC, Tschaharganeh DF: Multiplexed orthogonal genome editing and transcriptional activation by Cas12a. Nature Methods 2018:1

  • Ham O, Jin W, Lei L, Huang HH, Tsuji K, Huang M, Roh J, Rosenzweig A, Lu HAJ: Pathological cardiac remodeling occurs early in CKD mice from unilateral urinary obstruction, and is attenuated by Enalapril. Scientific Reports 2018, 8:16087; [Free Article]

  • Heim JR, Weston DP, Major K, Poynton H, Hartz KEH, Lydy MJ: Are there fitness costs of adaptive pyrethroid resistance in the amphipod, Hyalella azteca? Environmental Pollution 2018, 235:39-46;

  • Li P, Marino MP, Zou J, Argaw T, Morreale MT, Iaffaldano BJ, Reiser J: Efficiency and specificity of targeted integration mediated by the AAV2 Rep 78 protein. Human Gene Therapy 2018

  • O'Geen H, Ren C, Coggins NB, Bates SL, Segal DJ: Unexpected binding behaviors of bacterial Argonautes in human cells cast doubts on their use as targetable gene regulators. PloS one 2018, 13:e0193818

  • Osterbaan LJ, Schmitt-Keichinger C, Vigne E, Fuchs M: Optimal systemic grapevine fanleaf virus infection in Nicotiana benthamiana following agroinoculation. Journal of Virological Methods 2018

  • Parekkadan B, Tosi L, Larman HB: Long Adapter Single Stranded Oligonucleotide (LASSO) Probes to Capture and Clone Complex Libraries. Google Patents; 2018.

  • Pasin F, Tseng X-A, Bedoya LC, Heydarnejad J, Deng T-C, Garc a JA, Chen Y-R: Streamlined generation of plant virus infectious clones using the pLX mini binary vectors. Journal of Virological Methods 2018

  • Prado-Irwin SR, van de Schoot M, Geneva AJ: Detection and phylogenetic analysis of adenoviruses occurring in a single anole species. PeerJ 2018, 6:e5521; [Free Article]

  • Reynolds RG, Puente-Rol n AR, Castle AL, Van De Schoot M, Geneva AJ: Herpetofauna of Cay Sal Bank, Bahamas and Phylogenetic Relationships of Anolis fairchildi, Anolis sagrei, and Tropidophis curtus from the Region. Breviora 2018, 560:1-19

  • Skilton RJ, Wang Y, O'Neill C, Filardo S, Marsh P, B nard A, Thomson NR, Ramsey KH, Clarke IN: The Chlamydia muridarum plasmid revisited: new insights into growth kinetics. Wellcome Open Research 2018, 3

  • Tratar UL, Kos S, Kamensek U, Ota M, Tozon N, Sersa G, Cemazar M: Antitumor effect of antibiotic resistance gene-free plasmids encoding interleukin-12 in canine melanoma model. Cancer Gene Therapy 2018:1

2017

  • Cho YB, Jones SI, Vodkin LO: Mutations in Argonaute5 illuminate epistatic interactions of the K1 and I loci leading to saddle seed color patterns in Glycine max. The Plant Cell 2017:tpc. 00162.02017

  • Coggins NB, Stultz J, O'Geen H, Carvajal-Carmona LG, Segal DJ: Methods for Scarless, Selection-Free Generation of Human Cells and Allele-Specific Functional Analysis of Disease-Associated SNPs and Variants of Uncertain Significance. Scientific Reports (Nature Publisher Group) 2017, 7:1-9

  • Cox KH, Oliveira L, Plummer L, Corbin B, Gardella T, Balasubramanian R, Crowley WF: Modeling Mutant/Wild-type Interactions to Ascertain Pathogenicity of PROKR2 Missense Variants in Patients with Isolated GnRH Deficiency. Human Molecular Genetics 2017

  • Grigelioniene G, Nevalainen PI, Reyes M, Thiele S, Tafaj O, Molinaro A, Takatani R, Ala-Houhala M, Nilsson D, Eisfeldt J: A Large Inversion Involving GNAS Exon A/B and All Exons Encoding Gsα Is Associated with Autosomal Dominant Pseudohypoparathyroidism Type Ib (PHP1B). Journal of Bone and Mineral Research 2017

  • Kearns P, Fischer S, Fern ndez-Beaskoetxea S, Gabor C, Bosch J, Bowen JL, Tlusty MF, Woodhams D: Fighting fungi with fungi: the mycobiome contribution to emerging disease in amphibians. PeerJ Preprints 2017, 5:e3017v3011

  • Lee GQ, Orlova-Fink N, Einkauf K, Chowdhury FZ, Sun X, Harrington S, Kuo H-H, Hua S, Chen H-R, Ouyang Z: Clonal expansion of genome-intact HIV-1 in functionally polarized Th1 CD4+ T cells. The Journal of clinical investigation 2017, 127 [Free Article]

  • Major KM, Weston DP, Lydy MJ, Wellborn GA, Poynton HC: Unintentional exposure to terrestrial pesticides drives widespread and predictable evolution of resistance in freshwater crustaceans. Evolutionary Applications 2017

  • Mohsin J, P l T, Petersen JE, Darwish D, Ghazawi A, Ashraf T, Sonnevend A: Plasmid-Mediated Colistin Resistance Gene mcr-1 in an Escherichia coli ST10 Bloodstream Isolate in the Sultanate of Oman. Microbial Drug Resistance 2017

  • P l T, Ghazawi A, Darwish D, Villa L, Carattoli A, Hashmey R, Aldeesi Z, Jamal W, Rotimi V, Al-Jardani A: Characterization of NDM-7 Carbapenemase-Producing Escherichia coli Isolates in the Arabian Peninsula. Microbial Drug Resistance 2017

  • Park RJ, Wang T, Koundakjian D, Hultquist JF, Lamothe-Molina P, Monel B, Schumann K, Yu H, Krupzcak KM, Garcia-Beltran W: A genome-wide CRISPR screen identifies a restricted set of HIV host dependency factors. Nature Genetics 2017, 49:193; [Free Article]

  • Pianta A, Arvikar S, Strle K, Drouin EE, Wang Q, Costello CE, Steere AC: Evidence of the Immune Relevance of Prevotella copri, a Gut Microbe, in Patients With Rheumatoid Arthritis. Arthritis & Rheumatology 2017, 69:964-975

  • Reynolds RG, Strickland TR, Kolbe JJ, Falk BG, Perry G, Revell LJ, Losos JB: Archipelagic genetics in a widespread Caribbean anole. Journal of Biogeography 2017

  • Sonnevend , Yahfoufi N, Ghazawi A, Jamal W, Rotimi V, P l T: Contribution of horizontal gene transfer to the emergence of VIM-4 carbapenemase producer Enterobacteriaceae in Kuwait. Infection and drug resistance 2017, 10:469

  • Sriram S, Tran JA, Guo X, Hutcheon AE, Kazlauskas A, Zieske JD: Development of wound healing models to study TGFβ3's effect on SMA. Experimental Eye Research 2017

  • Sriram S, Tran JA, Guo X, Hutcheon AE, Lei H, Kazlauskas A, Zieske JD: PDGFRα Is a Key Regulator of T1 and T3's Differential Effect on SMA Expression in Human Corneal FibroblastsAbsence of PDGFRα Makes TGFB3 Stimulate SMA. Investigative Ophthalmology & Visual Science 2017, 58:1179-1186

  • Tidball AM, Dang LT, Glenn TW, Kilbane EG, Klarr DJ, Margolis JL, Uhler MD, Parent JM: Rapid Generation of Human Genetic Loss-of-Function iPSC Lines by Simultaneous Reprogramming and Gene Editing. Stem Cell Reports 2017

  • Zegpi R, Breedlove C, van Santen VL, Rasmussen C, Toro H: Kidney Cell-Adapted Infectious Bronchitis ArkDPI Vaccine is Stable and Protective. Avian Diseases 2017

2016

  • Andrade-Dom nguez A, Kolter R: Complete Genome Sequence of Pseudomonas aeruginosa Phage AAT-1. Genome Announcements 2016, 4:e00165-00116; [Free Article]

  • Bhardwaj P, Ziegler E, Palmer KL: Chlorhexidine induces VanA-type vancomycin resistance genes in enterococci. Antimicrobial agents and chemotherapy 2016, 60:2209-2221;

  • Bonazza C, Andrade SS, Sumikawa JT, Batista FP, Paredes-Gamero EJ, Gir o MJ, Oliva MLV, Castro RA: Primary Human Uterine Leiomyoma Cell Culture Quality Control: Some Properties of Myometrial Cells Cultured under Serum Deprivation Conditions in the Presence of Ovarian Steroids. PloS one 2016, 11:e0158578; [Free Article]

  • Burgess BJ, O'Malley JT, Kamakura T, Kristiansen K, Robertson NG, Morton C, Nadol Jr J: Histopathology of the Human Inner Ear in the p. L114P COCH Mutation (DFNA9). Audiology and Neurotology 2016, 21:88-97

  • Dooley K, Devalliere J, Uygun BE, Yarmush ML: Functionalized biopolymer particles enhance performance of a tissue-protective peptide under proteolytic and thermal stress. Biomacromolecules 2016

  • Duan Y, Ma G, Huang X, D'Amore PA, Zhang F, Lei H: The CRISPR/Cas9-created MDM2 T309G enhances vitreous-induced expression of MDM2 and proliferation and survival of cells. Journal of Biological Chemistry 2016:jbc. M116. 729467

  • Elbaz J, Yin P, Voigt CA: Genetic encoding of DNA nanostructures and their self-assembly in living bacteria. Nature communications 2016, 7

  • Joung KJ, Tsai S: Using RNA-guided FokI Nucleases (RFNs) to Increase Specificity for RNA-Guided Genome Editing. US Patent 20,160,153,003; 2016.

  • Lubitz CC, Parangi S, Holm TM, Bernasconi MJ, Schalck AP, Suh H, Economopoulos KP, Gunda V, Donovan SE, Sadow PM, Wirth LJ, Sullivan RJ, Panka DJ: Detection of Circulating BRAF(V600E) in Patients with Papillary Thyroid Carcinoma. J Mol Diagn 2016, 18:100-108.

  • Men C: Sequence-Specific Suppression of Alleles Causing Dominantly Inherited Retinal Degeneration Using the RNA-Guided Nuclease Cas9. 2016.

  • Pianta A, Arvikar S, Strle K, Drouin EE, Wang Q, Costello CE, Steere AC: Evidence for Immune Relevance of Prevotella copri, a Gut Microbe, in Patients with Rheumatoid Arthritis. Arthritis & Rheumatology 2016

  • Reynolds RG, Collar DC, Pasachnik SA, Niemiller ML, Puente-Rolón AR, Revell LJ: Ecological specialization and morphological diversification in greater antillean boas. Evolution 2016

  • Reynolds RG, Puente-Rolón AR, Geneva AJ, Aviles-Rodriguez KJ, Herrmann NC: Discovery of a Remarkable New Boa from the Conception Island Bank, Bahamas. Breviora 2016, 549:1-19

  • Saha SK, Gordan JD, Kleinstiver BP, Vu P, Najem MS, Yeo J-C, Shi L, Kato Y, Levin RS, Webber JT: Isocitrate dehydrogenase mutations confer dasatinib hypersensitivity and SRC-dependence in intrahepatic cholangiocarcinoma. Cancer Discovery 2016:CD-15-1442

  • Scola SE, Cornely K: Mutation of Surface Histidines inHaemophilus influenzaeCarbonic Anhydrase to Enable Purification by Metal Affinity Chromatography. 2016

  • Shin JW, Kim K-H, Chao MJ, Atwal RS, Gillis T, MacDonald ME, Gusella JF, Lee J-M: Permanent inactivation of Huntington's disease mutation by personalized allele-specific CRISPR/Cas9. Human Molecular Genetics 2016:ddw286

  • Siliceo-Cantero HH, Garcia A, Reynolds RG, Pacheco G, Lister BC: Dimorphism and Divergence in Island and Mainland Anoles. Biological Journal of the Linnean Society 2016

  • Sonnevend , Ghazawi A, Alqahtani M, Shibl A, Jamal W, Hashmey R, Pal T: Plasmid-mediated colistin resistance in Escherichia coli from the Arabian Peninsula. International Journal of Infectious Diseases 2016

  • W Gillespie J, Wei L, A Petrenko V: Selection of Lung Cancer-Specific Landscape Phage for Targeted Drug Delivery. Combinatorial chemistry & high throughput screening 2016, 19:412-422

  • Wein MN, Liang Y, Goransson O, Sundberg TB, Wang J, Williams EA, O'meara MJ, Govea N, Beqo B, Nishimori S: SIKs control osteocyte responses to parathyroid hormone. Nature Communications 2016, 7:13176; [Free Article]

  • Winchell KM, Reynolds RG, Prado-Irwin SR, Puente-Rolón AR, Revell LJ: Phenotypic shifts in urban areas in the tropical lizard Anolis cristatellus. Evolution 2016

2015

  • Adams HM, Li X, Mascio C, Chesnel L, Palmer KL: Mutations Associated with Reduced Surotomycin Susceptibility in Clostridium difficile and Enterococcus Species. Antimicrobial Agents and Chemotherapy 2015, 59:4139-4147. [Free Article]

  • Bushar LM, Reynolds RG, Tucker S, Pace LC, Lutterschmidt WI, Odum RA, Reinert HK: Genetic Characterization of an Invasive Boa constrictor Population on the Caribbean Island of Aruba. Journal of Herpetology 2015, 49:602-610.

  • Chen L, Tian Y, Chen S, Liesenfeld O: Performance of the cobas ® influenza A/B assay for rapid PCR-based detection of influenza compared to Prodesse ProFlu+ and viral culture. European Journal of Microbiology and Immunology 2015, 5:236-245. [Free Article]

  • Chokshi RH, Larsen AT, Bhayana B, Cotten JF: Breathing Stimulant Compounds Inhibit TASK-3 Potassium Channel Function Likely by Binding at a Common Site in the Channel Pore. Mol Pharmacol 2015, 88:926-934.

  • Dey-Guha I, Alves CP, Yeh AC, Salony, Sole X, Darp R, Ramaswamy S: A Mechanism for Asymmetric Cell Division Resulting in Proliferative Asynchronicity. Molecular Cancer Research 2015, 13:223-230. [Free Article]

  • Dib B, Lin H, Maidana DE, Tian B, Miller JB, Bouzika P, Miller JW, Vavvas DG: Mitochondrial DNA has a pro-inflammatory role in AMD. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 2015, 1853:2897-2906.

  • Gautam V, D'Avanzo C, Berezovska O, Tanzi RE, Kovacs DM: Synaptotagmins interact with APP and promote Abeta generation. Mol Neurodegener 2015, 10:31. [Free Article]

  • Griffin MJ, Reichley SR, Greenway TE, Quiniou SM, Ware C, Gao DX, Gaunt PS, Yanong RP, Pouder DB, Hawke JP, Soto E: Comparison of Edwardsiella ictaluri isolates from different hosts and geographic origins. J Fish Dis 2015.

  • Gultekin Y, Eren E, Ozoren N: Overexpressed NLRC3 acts as an anti-inflammatory cytosolic protein. J Innate Immun 2015, 7:25-36.

  • Hawver LA, Tehrani M, Antczak NM, Kania D, Muser S, Sefcikova J, Beuning PJ: Point mutations in Escherichia coli DNA pol V that confer resistance to non-cognate DNA damage also alter protein-protein interactions. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 2015, 780:1-14.

  • Huang J, Jiao J, Xu W, Zhao H, Zhang C, Shi Y, Xiao Z: miR-155 is upregulated in patients with active tuberculosis and inhibits apoptosis of monocytes by targeting FOXO3. Mol Med Rep 2015, 12:7102-7108.

  • Huo W, Adams HM, Zhang MQ, Palmer KL: Genome Modification in Enterococcus faecalis OG1RF Assessed by Bisulfite Sequencing and Single-Molecule Real-Time Sequencing. J Bacteriol 2015, 197:1939-1951. [Free Article]

  • Kearns PJ, Angell JH, Feinman SG, Bowen JL: Long-term nutrient addition differentially alters community composition and diversity of genes that control nitrous oxide flux from salt marsh sediments. Estuarine, Coastal and Shelf Science 2015, 154:39-47.

  • Lei H, Qian CX, Lei J, Haddock LJ, Mukai S, Kazlauskas A: RasGAP Promotes Autophagy and Thereby Suppresses Platelet-Derived Growth Factor Receptor-Mediated Signaling Events, Cellular Responses, and Pathology. Mol Cell Biol 2015, 35:1673-1685.

  • Lutful Kabir FM, DeInnocentes P, Bird RC: Altered microRNA Expression Profiles and Regulation of INK4A/CDKN2A Tumor Suppressor Genes in Canine Breast Cancer Models. J Cell Biochem 2015, 116:2956-2969.

  • Lyons C, Raustad N, Bustos MA, Shiaris M: Incidence of Type II CRISPR1-Cas Systems in Enterococcus Is Species-Dependent. PLoS One 2015, 10:e0143544. [Free Article]

  • Mauris J, Dieckow J, Schob S, Pulli B, Hatton MP, Jeong S, Bauskar A, Gabison E, Nowak R, Argüeso P: Loss of CD147 results in impaired epithelial cell differentiation and malformation of the meibomian gland. Cell Death Dis 2015, 6:e1726. [Free Article]

  • Molinaro A, Tiosano D, Takatani R, Chrysis D, Russell W, Koscielniak N, Kottler ML, Agretti P, De Marco G, Ahtiainen P, Christov M, Makitie O, Tonacchera M, Juppner H: TSH elevations as the first laboratory evidence for pseudohypoparathyroidism type Ib (PHP-Ib). J Bone Miner Res 2015, 30:906-912. [Free Article]

  • Niederst MJ, Hu H, Mulvey HE, Lockerman EL, Garcia AR, Piotrowska Z, Sequist LV, Engelman JA: The Allelic Context of the C797S Mutation Acquired upon Treatment with Third-Generation EGFR Inhibitors Impacts Sensitivity to Subsequent Treatment Strategies. Clin Cancer Res 2015, 21:3924-3933. [Free Article]

  • Piotrowska Z, Niederst MJ, Karlovich CA, Wakelee HA, Neal JW, Mino-Kenudson M, Fulton L, Hata AN, Lockerman EL, Kalsy A, Digumarthy S, Muzikansky A, Raponi M, Garcia AR, Mulvey HE, Parks MK, DiCecca RH, Dias-Santagata D, Iafrate AJ, Shaw AT, Allen AR, Engelman JA, Sequist LV: Heterogeneity Underlies the Emergence of EGFRT790 Wild-Type Clones Following Treatment of T790M-Positive Cancers with a Third-Generation EGFR Inhibitor. Cancer Discov 2015, 5:713-722. [Free Article]

  • Reynolds RG, Puente-Rolón AR, Platenberg R, Tyler RK, Tolson PJ, Revell LJ: Large divergence and low diversity suggest genetically informed conservation strategies for the endangered Virgin Islands Boa (Chilabothrus monensis). Global Ecology and Conservation 2015, 3:487-502.

  • Samoylov A, Cochran A, Schemera B, Kutzler M, Donovan C, Petrenko V, Bartol F, Samoylova T: Humoral immune responses against gonadotropin releasing hormone elicited by immunization with phage-peptide constructs obtained via phage display. Journal of Biotechnology 2015, 216:20-28.

  • Scavotto RE, Dziallas C, Bentzon-Tilia M, Riemann L, Moisander PH: Nitrogen-fixing bacteria associated with copepods in coastal waters of the North Atlantic Ocean. Environ Microbiol 2015, 17:3754-3765.

  • Shoemaker KM, Moisander PH: Microbial diversity associated with copepods in the North Atlantic subtropical gyre. FEMS Microbiol Ecol 2015, 91.

  • Takatani R, Minagawa M, Molinaro A, Reyes M, Kinoshita K, Takatani T, Kazukawa I, Nagatsuma M, Kashimada K, Sato K, Matsushita K, Nomura F, Shimojo N, Juppner H: Similar frequency of paternal uniparental disomy involving chromosome 20q (patUPD20q) in Japanese and Caucasian patients affected by sporadic pseudohypoparathyroidism type Ib (sporPHP1B). Bone 2015, 79:15-20.

  • Takatani R, Molinaro A, Grigelioniene G, Tafaj O, Watanabe T, Reyes M, Sharma A, Singhal V, Raymond FL, Linglart A, Juppner H: Analysis of Multiple Families with Single Individuals Affected by Pseudohypoparathyroidism Type Ib (PHP1B) Reveals Only One Novel Maternally Inherited GNAS Deletion. J Bone Miner Res 2015.

  • Zhang Z, Fang Y, Wang Q, Sun Y, Xiong C, Cao L, Wang B, Bao N, Zhao J: Tumor necrosis factor-like weak inducer of apoptosis regulates particle-induced inflammatory osteolysis via the p38 mitogen-activated protein kinase signaling pathway. Mol Med Rep 2015, 12:1499-1505.

2014

  • Baker JM, Boyce FM: High-throughput Functional Screening using a Homemade Dual-glow Luciferase Assay. Journal of Visualized Experiments 2014.

  • Biller SJ, Berube PM, Berta-Thompson JW, Kelly L, Roggensack SE, Awad L, Roache-Johnson KH, Ding H, Giovannoni SJ, Rocap G, Moore LR, Chisholm SW: Genomes of diverse isolates of the marine cyanobacterium Prochlorococcus. Sci Data 2014, 1:140034. [Free Article]

  • Dostalova Z, Zhou X, Liu A, Zhang X, Zhang Y, Desai R, Forman SA, Miller KW: Human alpha1beta3gamma2L gamma-aminobutyric acid type A receptors: High-level production and purification in a functional state. Protein Sci 2014, 23:157-166. [Free Article]

  • Ferdman J, Porcheray F, Gao B, Moore C, DeVito J, Dougherty S, Thomas MV, Farkash EA, Elias N, Kawai T, Malek SK, Tullius SG, Wong W, Zorn E: Expansion and somatic hypermutation of B-cell clones in rejected human kidney grafts. Transplantation 2014, 98:766-772. [Free Article]

  • Gautam V, D'Avanzo C, Hebisch M, Kovacs DM, Kim DY: BACE1 activity regulates cell surface contactin-2 levels. Mol Neurodegener 2014, 9:4. [Free Article]

  • Ghetas A, Thaxton G, Breedlove C, van Santen V, Toro H: Effects of Adaptation of Infectious Bronchitis Virus Arkansas Attenuated Vaccine to Embryonic Kidney Cells. Avian diseases 2014, 59:106-113

  • Lin MV, Charlton AN, Rouster SD, Zamor PJ, Sherman KE: Hepatitis C virus NS3 mutations in haemophiliacs. Haemophilia 2014, 20:659-665. [Free Article]

  • Reynolds RG, Puente-Rolón AR, Kolodzaike K, Butler-Smith T: Isolation and characterization of 23 novel polymorphic microsatellite markers from the endangered Puerto Rican boa (Chilabothrus inornatus) using paired-end Illumina shotgun sequencing. Conservation Genetics Resources 2014, 6:107-109.

  • Villet RA, Truong-Bolduc QC, Wang Y, Estabrooks Z, Medeiros H, Hooper DC: Regulation of expression of abcA and its response to environmental conditions. J Bacteriol 2014, 196:1532-1539. [Free Article]

  • Yuksel S, Eren E, Hatemi G, Sahillio lu AC, Gultekin Y, Demiroz D, Akdis C, Fresko I, Ozoren N: Novel NLRP3/cryopyrin mutations and pro-inflammatory cytokine profiles in Behcet's syndrome patients. International Immunology 2014, 26:71-81.

2013

  • Arystarkhova E, Liu YB, Salazar C, Stanojevic V, Clifford RJ, Kaplan JH, Kidder GM, Sweadner KJ: Hyperplasia of Pancreatic Beta Cells and Improved Glucose Tolerance in Mice Deficient in the FXYD2 Subunit of Na,K-ATPase. Journal of Biological Chemistry 2013, 288:7077-7085. [Free Article]

  • Clarke MSF, Sundaresan A, Vanderburg CR, Banigan MG, Pellis NR: A three-dimensional tissue culture model of bone formation utilizing rotational co-culture of human adult osteoblasts and osteoclasts. Acta Biomaterialia 2013, 9:7908-7916.

  • Dai N, Christiansen J, Nielsen FC, Avruch J: mTOR complex 2 phosphorylates IMP1 cotranslationally to promote IGF2 production and the proliferation of mouse embryonic fibroblasts. Genes & Development 2013, 27:301-312. [Free Article]

  • Fu Y, Foden JA, Khayter C, Maeder ML, Reyon D, Joung JK, Sander JD: High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells. Nat Biotechnol 2013, 31:822-826. [Free Article]

  • Gunda V, Cogdill AP, Bernasconi MJ, Wargo JA, Parangi S: Potential role of 5-Aza-2'-deoxycytidine induced MAGE-A4 expression in immunotherapy for anaplastic thyroid cancer. Surgery 2013, 154:1456-1462. [Free Article]

  • Hwang WY, Fu Y, Reyon D, Maeder ML, Kaini P, Sander JD, Joung JK, Peterson RT, Yeh JR: Heritable and precise zebrafish genome editing using a CRISPR-Cas system. PLoS One 2013, 8:e68708. [Free Article]

  • Jacobo SMP, DeAngelis MM, Kim IK, Kazlauskas A: Age-Related Macular Degeneration-Associated Silent Polymorphisms in HtrA1 Impair Its Ability To Antagonize Insulin-Like Growth Factor 1. Molecular and Cellular Biology 2013, 33:1976-1990. [Free Article]

  • Kwak H-H, Park K-M, Nam H-S, Park S-M, Woo H-M: Disparate Hypervariable Region-1 of Mitochondrial DNA Did Not Induce Skin Allograft Rejection in Cloned Porcine Models. Transplantation Proceedings 2013, 45:1787-1791.

  • Kwak YG, Truong-Bolduc QC, Kim HB, Song K-H, Kim ES, Hooper DC: Association of norB overexpression and fluoroquinolone resistance in clinical isolates of Staphylococcus aureus from Korea. Journal of Antimicrobial Chemotherapy 2013:dkt286. [Free Article]

  • Maeder ML, Angstman JF, Richardson ME, Linder SJ, Cascio VM, Tsai SQ, Ho QH, Sander JD, Reyon D, Bernstein BE, Costello JF, Wilkinson MF, Joung JK: Targeted DNA demethylation and activation of endogenous genes using programmable TALE-TET1 fusion proteins. Nat Biotechnol 2013, 31:1137-1142. [Free Article]

  • Mauris J, Mantelli F, Woodward AM, Cao Z, Bertozzi CR, Panjwani N, Godula K, Argüeso P: Modulation of ocular surface glycocalyx barrier function by a galectin-3 N-terminal deletion mutant and membrane-anchored synthetic glycopolymers. PloS one 2013, 8:e72304. [Free Article]

  • Palomares RA, Marley SM, Givens MD, Gallardo RA, Brock KV: Bovine viral diarrhea virus fetal persistent infection after immunization with a contaminated modified-live virus vaccine. Theriogenology 2013, 79:1184-1195.

  • Puente-Rolón AR, Reynolds RG, Revell LJ: Preliminary Genetic Analysis Supports Cave Populations as Targets for Conservation in the Endemic Endangered Puerto Rican Boa (Boidae: Epicrates inornatus ). PLOS ONE 2013, 8:e63899. [Free Article]

  • Reynolds RG, Niemiller ML, Hedges SB, Dornburg A, Puente-Rolón AR, Revell LJ: Molecular phylogeny and historical biogeography of West Indian boid snakes (Chilabothrus). Molecular Phylogenetics and Evolution 2013, 68:461-470.

  • Reynolds RG, Puente-Rolón AR, Reed RN, Revell LJ: Genetic analysis of a novel invasion of Puerto Rico by an exotic constricting snake. Biological Invasions 2013, 15:953-959.

  • Saur T, DeMarco SE, Ortiz A, Sliwoski GR, Hao L, Wang X, Cohen BM, Buttner EA: A genome-wide RNAi screen in Caenorhabditis elegans identifies the nicotinic acetylcholine receptor subunit ACR-7 as an antipsychotic drug target. PLoS Genet 2013, 9:e1003313. [Free Article]

  • Zhang X, Rice K, Wang Y, Chen W, Zhong Y, Nakayama Y, Zhou Y, Klibanski A: Maternally Expressed Gene 3 (MEG3) Noncoding Ribonucleic Acid: Isoform Structure, Expression, and Functions. Endocrinology 2013.

2012

  • Aly SA, Debavalya N, Suh S-J, Oryazabal OA, Boothe DM: Molecular mechanisms of antimicrobial resistance in fecal Escherichia coli of healthy dogs after enrofloxacin or amoxicillin administration. Canadian Journal of Microbiology 2012, 58:1288-1294.

  • Fagbohun OA, Bedi D, Grabchenko NI, Deinnocentes PA, Bird RC, Petrenko VA: Landscape phages and their fusion proteins targeted to breast cancer cells. Protein Engineering Design and Selection 2012, 25:271-283. [Free Article]

  • Gallardo RA, van Santen VL, Toro H: Effects of chicken anaemia virus and infectious bursal disease virus-induced immunodeficiency on infectious bronchitis virus replication and genotypic drift. Avian Pathology 2012, 41:451-458.

  • Kos VN, Desjardins CA, Griggs A, Cerqueira G, Van Tonder A, Holden MTG, Godfrey P, Palmer KL, Bodi K, Mongodin EF, Wortman J, Feldgarden M, Lawley T, Gill SR, Haas BJ, Birren B, Gilmore MS: Comparative Genomics of Vancomycin-Resistant Staphylococcus aureus Strains and Their Positions within the Clade Most Commonly Associated with Methicillin-Resistant S. aureus Hospital-Acquired Infection in the United States. mBio 2012, 3:e00112-00112-e00112-00112. [Free Article]

  • Maison SF, Liu XP, Eatock RA, Sibley DR, Grandy DK, Liberman MC: Dopaminergic signaling in the cochlea: receptor expression patterns and deletion phenotypes. J Neurosci 2012, 32:344-355. [Free Article]

  • Moore FE, Reyon D, Sander JD, Martinez SA, Blackburn JS, Khayter C, Ramirez CL, Joung JK, Langenau DM: Improved somatic mutagenesis in zebrafish using transcription activator-like effector nucleases (TALENs). PLoS One 2012, 7:e37877.

  • Muhammed M, Fuchs BB, Wu MP, Breger J, Coleman JJ, Mylonakis E: The role of mycelium production and a MAPK-mediated immune response in the C. elegans-Fusarium model system. Medical Mycology 2012, 50:488-496. [Free Article]

  • Ndegwa EN, Joiner KS, Toro H, Van Ginkel FW, Van Santen VL: The proportion of specific viral subpopulations in attenuated Arkansas Delmarva Poultry Industry infectious bronchitis vaccines influences vaccination outcome. Avian diseases 2012, 56:642-653

  • Porcheray F, DeVito J, Helou Y, Dargon I, Fraser JW, Nobecourt P, Ferdman J, Germana S, Girouard TC, Kawai T, Saidman SL, Wong W, Colvin RB, Leguern C, Zorn E Expansion of Polyreactive B Cells Cross-Reactive to HLA and Self in the Blood of a Patient With Kidney Graft Rejection: Polyreactive Antibodies in Humoral Rejection. American Journal of Transplantation 2012, 12:2088-2097.

  • Ramirez CL, Certo MT, Mussolino C, Goodwin MJ, Cradick TJ, McCaffrey AP, Cathomen T, Scharenberg AM, Joung JK: Engineered zinc finger nickases induce homology-directed repair with reduced mutagenic effects. Nucleic Acids Research 2012, 40:5560-5568. [Free Article]

  • Ruan GX, Kazlauskas A: Axl is essential for VEGF-A-dependent activation of PI3K/Akt. EMBO J 2012, 31:1692-1703. [Free Article]

  • Tamang DL, Pirzai W, Priebe GP, Traficante DC, Pier GB, Falck JR, Morisseau C, Hammock BD, McCormick BA, Gronert K, Hurley BP: Hepoxilin A3 Facilitates Neutrophilic Breach of Lipoxygenase-Expressing Airway Epithelial Barriers. The Journal of Immunology 2012, 189:4960-4969. [Free Article]

  • Toro H, Pennington D, Gallardo RA, van Santen VL, van Ginkel FW, Zhang J, Joiner KS: Infectious Bronchitis Virus Subpopulations in Vaccinated Chickens After Challenge. Avian Diseases 2012, 56:501-508.

  • Yu Y, Sanderson SR, Reyes M, Sharma A, Dunbar N, Srivastava T, Jüppner H, Bergwitz C: Novel NaPi-IIc mutations causing HHRH and idiopathic hypercalciuria in several unrelated families: Long-term follow-up in one kindred. Bone 2012, 50:1100-1106. [Free Article]

2011

  • Alter G, Heckerman D, Schneidewind A, Fadda L, Kadie CM, Carlson JM, Oniangue-Ndza C, Martin M, Li B, Khakoo SI, Carrington M, Allen TM, Altfeld M: HIV-1 adaptation to NK-cell-mediated immune pressure. Nature 2011, 476:96-100. [Free Article]

  • Coleman JJ, Muhammed M, Kasperkovitz PV, Vyas JM, Mylonakis E: Fusarium pathogenesis investigated using Galleria mellonella as a heterologous host. Fungal Biology 2011, 115:1279-1289. [Free Article]

  • Faber AC, Corcoran RB, Ebi H, Sequist LV, Waltman BA, Chung E, Incio J, Digumarthy SR, Pollack SF, Song Y, Muzikansky A, Lifshits E, Roberge S, Coffman EJ, Benes CH, Gomez HL, Baselga J, Arteaga CL, Rivera MN, Dias-Santagata D, Jain RK, Engelman JA: BIM expression in treatment-naive cancers predicts responsiveness to kinase inhibitors. Cancer Discov 2011, 1:352-365. [Free Article]

  • Hawver LA, Gillooly CA, Beuning PJ: Characterization of Escherichia coli UmuC Active-Site Loops Identifies Variants That Confer UV Hypersensitivity. Journal of Bacteriology 2011, 193:5400-5411. [Free Article]

  • Jeong H, Cohen DE, Cui L, Supinski A, Savas JN, Mazzulli JR, Yates JR, Bordone L, Guarente L, Krainc D: Sirt1 mediates neuroprotection from mutant huntingtin by activation of the TORC1 and CREB transcriptional pathway. Nature Medicine 2011, 18:159-165. [Free Article]

  • Lei H, Velez G, Kazlauskas A: Pathological signaling via platelet-derived growth factor receptor Α involves chronic activation of Akt and suppression of p53. Molecular and cellular biology 2011, 31:1788-1799. [Free Article]

  • Liu Z, Segawa H, Aydin C, Reyes M, Erben RG, Weinstein LS, Chen M, Marshansky V, Fröhlich LF, Bastepe M: Transgenic Overexpression of the Extra-Large GsΑ Variant XLΑs Enhances GsΑ-Mediated Responses in the Mouse Renal Proximal Tubule in Vivo. Endocrinology 2011, 152:1222-1233.

  • Palmer KL, Daniel A, Hardy C, Silverman J, Gilmore MS: Genetic Basis for Daptomycin Resistance in Enterococci. Antimicrobial Agents and Chemotherapy 2011, 55:3345-3356. [Free Article]

  • Phulwani P, Bergwitz C, Jaureguiberry G, Rasoulpour M, Estrada E: Hereditary hypophosphatemic rickets with hypercalciuria and nephrolithiasis-Identification of a novel SLC34A3/NaPi-IIc mutation. American Journal of Medical Genetics Part A 2011, 155:626-633.

  • Raytcheva DA, Haase-Pettingell C, Piret JM, King JA: Intracellular Assembly of Cyanophage Syn5 Proceeds through a Scaffold-Containing Procapsid. Journal of Virology 2011, 85:2406-2415. [Free Article]

  • Somarowthu S, Brodkin HR, D'Aquino JA, Ringe D, Ondrechen MJ, Beuning PJ: A Tale of Two Isomerases: Compact versus Extended Active Sites in Ketosteroid Isomerase and Phosphoglucose Isomerase. Biochemistry 2011, 50:9283-9295.

  • Spencer RJ, del Rosario BC, Pinter SF, Lessing D, Sadreyev RI, Lee JT: A Boundary Element Between Tsix and Xist Binds the Chromatin Insulator Ctcf and Contributes to Initiation of X-Chromosome Inactivation. Genetics 2011, 189:441-454. [Free Article]

  • Sweadner KJ, Pascoa JL, Salazar CA, Arystarkhova E: Post-transcriptional Control of Na,K-ATPase Activity and Cell Growth by a Splice Variant of FXYD2 Protein with Modified mRNA. Journal of Biological Chemistry 2011, 286:18290-18300. [Free Article]

  • Vallabhajosyula P, Tena A, Yamada K, Sachs DH: Signal Joint T-Cell Receptor Excision Circle Assay in Miniature Swine. Transplantation 2011, 92:634-640. [Free Article]

2010

  • Chillambhi S, Turan S, Hwang D-Y, Chen H-C, Jüppner H, Bastepe M: Deletion of the Noncoding GNAS Antisense Transcript Causes Pseudohypoparathyroidism Type Ib and Biparental Defects of GNAS Methylation in cis. The Journal of Clinical Endocrinology & Metabolism 2010, 95:3993-4002.

  • Dostalova Z, Liu A, Zhou X, Farmer SL, Krenzel ES, Arevalo E, Desai R, Feinberg-Zadek PL, Davies PA, Yamodo IH, Forman SA, Miller KW: High-level expression and purification of Cys-loop ligand-gated ion channels in a tetracycline-inducible stable mammalian cell line: GABA A and serotonin receptors: Over-Expression of Neuronal Cys-Loop Receptors. Protein Science 2010, 19:1728-1738. [Free Article]

  • Fritz S, Fernández-del Castillo C, Iafrate AJ, Mino-Kenudson M, Neyhard N, LaFemina J, Stirman A, Warshaw AL, Thayer SP: Novel Xenograft and Cell Line Derived From an Invasive Intraductal Papillary Mucinous Neoplasm of the Pancreas Give New Insights Into Molecular Mechanisms:. Pancreas 2010, 39:308-314. [Free Article]

  • Gallardo RA, Van Santen VL, Toro H: Host intraspatial selection of infectious bronchitis virus populations. Avian diseases 2010, 54:807-813

  • Hurley BP, Goodman AL, Mumy KL, Murphy P, Lory S, McCormick BA: The two-component sensor response regulator RoxS/RoxR plays a role in Pseudomonas aeruginosa interactions with airway epithelial cells. Microbes and Infection 2010, 12:190-198. [Free Article]

  • Malo MS, Alam SN, Mostafa G, Zeller SJ, Johnson PV, Mohammad N, Chen KT, Moss AK, Ramasamy S, Faruqui A, Hodin S, Malo PS, Ebrahimi F, Biswas B, Narisawa S, Millan JL, Warren HS, Kaplan JB, Kitts CL, Hohmann EL, Hodin RA: Intestinal alkaline phosphatase preserves the normal homeostasis of gut microbiota. Gut 2010, 59:1476-1484.

  • Palmer KL, Gilmore MS: Multidrug-Resistant Enterococci Lack CRISPR-cas. mBio 2010, 1:e00227-00210-e00227-00219. [Free Article]

  • Shen H-Y, Zhao Y, Chen X-Y, Xiong R-P, Lu J-L, Chen J-F, Chen L-Y, Zhou Y-G: Differential Alteration of Heat Shock Protein 90 in Mice Modifies Glucocorticoid Receptor Function and Susceptibility to Trauma. Journal of Neurotrauma 2010, 27:373-381.

  • Szostak JW: DNA ends: just the beginning (Nobel lecture). Angewandte Chemie International Edition 2010, 49:7386-7404

  • Zhang S, Wang F, Keats J, Ning Y, Wardwell SD, Moran L, Mohemmad QK, Ye E, Anjum R, Wang Y: AP26113, a potent ALK inhibitor, overcomes mutations in EML4-ALK that confer resistance to PF-02341066. In Proceedings of the 101st Annual Meeting of the American Association for Cancer Research. 2010: 17-21.

  • Zhou Y, Cheunsuchon P, Nakayama Y, Lawlor MW, Zhong Y, Rice KA, Zhang L, Zhang X, Gordon FE, Lidov HGW, Bronson RT, Klibanski A: Activation of paternally expressed genes and perinatal death caused by deletion of the Gtl2 gene. Development 2010, 137:2643-2652. [Free Article]

2009

  • Aydin C, Aytan N, Mahon MJ, Tawfeek HA, Kowall NW, Dedeoglu A, Bastepe M: Extralarge XLΑs (XXLΑs), a variant of stimulatory G protein Α-subunit (GsΑ), is a distinct, membrane-anchored GNAS product that can mimic GsΑ. Endocrinology 2009, 150:3567-3575.

  • Brown LCW, Acker MG, Clardy J, Walsh CT, Fischbach MA: Thirteen posttranslational modifications convert a 14-residue peptide into the antibiotic thiocillin. Proceedings of the National Academy of Sciences 2009, 106:2549-2553.

  • Chan Y-M, Guillebon Ad, Lang-Muritano M, Plummer L, Cerrato F, Tsiaras S, Gaspert A, Lavoie HB, Wu C-H, Crowley WF, Amory JK, Pitteloud N, Seminara SB: GNRH1 mutations in patients with idiopathic hypogonadotropic hypogonadism. Proceedings of the National Academy of Sciences 2009, 106:11703-11708. [Free Article]

  • Hanekamp JS, Okumi M, Tena A, Arn S, Yamada K, Sachs DH: Cytoplasmic Inheritance of Transplantation Antigens in Animals Produced by Nuclear Transfer:. Transplantation 2009, 88:30-37. [Free Article]

  • Jones KL, McHugh GA, Glickstein LJ, Steere AC: Analysis of Borrelia burgdorferi genotypes in patients with lyme arthritis: High frequency of ribosomal RNA intergenic spacer type 1 strains in antibiotic-refractory arthritis. Arthritis & Rheumatism 2009, 60:2174-2182.

  • Kim YB: Improved trimethoprim-resistance cassette for prokaryotic selections. Journal of Bioscience and Bioengineering 2009, 108:441-445.

  • Hanekamp JS, Okumi M, Tena A, Arn S, Yamada K, Sachs DH: Cytoplasmic Inheritance of Transplantation Antigens in Animals Produced by Nuclear Transfer:. Transplantation 2009, 88:30-37. [Free Article]

  • Mahon MJ: The Parathyroid Hormone 1 Receptor Directly Binds to the FERM Domain of Ezrin, an Interaction that Supports Apical Receptor Localization and Signaling in LLC-PK1 Cells. Molecular Endocrinology 2009, 23:1691-1701.

  • Medoff BD, Landry AL, Wittbold KA, Sandall BP, Derby MC, Cao Z, Adams JC, Xavier RJ: CARMA3 Mediates Lysophosphatidic Acid-Stimulated Cytokine Secretion by Bronchial Epithelial Cells. American Journal of Respiratory Cell and Molecular Biology 2009, 40:286-294.

  • Quigley BR, Tropp BE: E. coli cardiolipin synthase: Function of N-terminal conserved residues. Biochimica et Biophysica Acta (BBA) - Biomembranes 2009, 1788:2107-2113.

  • Wang YE, Li B, Carlson JM, Streeck H, Gladden AD, Goodman R, Schneidewind A, Power KA, Toth I, Frahm N, Alter G, Brander C, Carrington M, Walker BD, Altfeld M, Heckerman D, Allen TM: Protective HLA Class I Alleles That Restrict Acute-Phase CD8+ T-Cell Responses Are Associated with Viral Escape Mutations Located in Highly Conserved Regions of Human Immunodeficiency Virus Type 1. Journal of Virology 2009, 83:1845-1855. [Free Article]