• Research Services

• Sanger DNA Sequencing
  • Overview
  
  
  • Individual Tube Sequencing
  
  
  • 96-Well Plate Sequencing
  
  
  • Difficult Template Sequencing
  
  
  • Long Read Sanger Sequencing
  
  
  • Supporting Sequencing Services
    
    • 96-Well PCR Product Purification
    
    
    • 96-Well Plasmid DNA Preparation
    
    
• Next-Generation Sequencing
  • Overview
  
  
  • CRISPR Sequencing
  
  
  • Complete Plasmid Sequencing
  
  
  • Viral Genome Sequencing
  
  
  • Complete Amplicon Sequencing
  
  
  • 16S Sequencing
  
  
  • Library Sequencing
  
  
• Nanopore Sequencing
  • Rapid Plasmid and Amplicon Sequencing
  
  
  • AAV Genome Sequencing
  
  
• Genotyping
  • Overview
  
  
  • Mouse Genotyping
  
  
  • DNA Fragment Analysis
• Laboratory Automation
  • Overview
  
  
  • 96-Well Plasmid DNA Preparation
  
  
  • cDNA Library Screening
  
  
  • Custom Projects
  
  
• Molecular Biology
  • Overview
  
  
  • Custom Services

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    New AAV Genome Sequencing
    Service

Posted on October 2, 2025

The CCIB DNA Core is pleased to offer our new direct rAAV sequencing of single-stranded vectors (ssAAV) using Oxford Nanopore long-read technology. With a quick turnaround time, our end-to-end service includes extraction of viral genomes from purified rAAV capsids, library preparation, sequencing and downstream analysis to support comprehensive vector validation and quality control.

Please follow this link for additional details.

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Effective October 1, 2025: Updated FY'26 Service Fees

Posted on September 26, 2025

Dear Core Users:

After consultation with MGB Research Finance Management, our FY'26 service fee structure has now been finalized and will go into effect as of October 1, 2025.

These fees support our continuous process improvement efforts and the implementation of additional and/or improved service features. The changes are mandated by Mass General Brigham policies, which dictate that cores recover their operating costs without generating excess revenue.

All orders that begin processing in September but complete on or after October 1, 2025, will be invoiced at current FY'25 pricing. Orders that are placed close to the end of September but are not processed before October 1, 2025, will be invoiced according to the updated FY'26 pricing structure.

We appreciate your past patronage and look forward to serving your future research needs.

Sincerely,
The CCIB DNA Core Team

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    New Library Sequencing
    Service

Posted on March 1, 2025

The DNA Core is pleased to offer our new Library Sequencing service. Using our Illumina NextSeq 1000 we will sequence your pre-made library with the recently released XLEAP-SBS chemistry and your choice of P1 (100M reads) or P2 (400M reads) flow cell to best meet your sequencing output needs.

Please follow this link for additional details.

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