News and Announcements
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ATTENTION!THE CCIB DNA CORE IS MOVING!
Posted on July 29, 2026
Effective Monday, August 17th 2026, the CCIB DNA Core will be operating out of a new space at the MGH Main Campus/Simches Research Building. Our courier service will still be picking up samples daily at the HMS, BWH, CNY, Ragon, and Jackson drop-off locations. Samples can also be placed in the drop-box in the Simches lobby. If shipping samples that will arrive after Friday, August 15th, please use the new address below:
MGH CCIB DNA Core
185 Cambridge Street, CPZN 7300
Boston, MA 02114
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New Full-Length Amplicon
Sequencig Service
Posted on January 16, 2026
The CCIB DNA Core is pleased to offer Full-Length Amplicon Sequencing using Oxford Nanopore long-read technology. This service differs from our rapid amplicon sequencing service by utilizing a non-fragmenting library preparation protocol, where each sequenced read corresponds to an entire amplicon molecule.
The delivered data include a consensus sequence in FASTA format for the resolved amplicon(s), raw sequencing reads in FASTQ format, and EXCEL files with per-base depth and coverage metrics.
Please follow this link for additional details.
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New AAV Genome Sequencing
Service
Posted on October 2, 2025
The CCIB DNA Core is pleased to offer our new direct rAAV sequencing of single-stranded vectors (ssAAV) using Oxford Nanopore long-read technology. With a quick turnaround time, our end-to-end service includes extraction of viral genomes from purified rAAV capsids, library preparation, sequencing and downstream analysis to support comprehensive vector validation and quality control.
Please follow this link for additional details.
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Effective October 1, 2025: Updated FY'26 Service Fees
Posted on September 26, 2025
Dear Core Users:
After consultation with MGB Research Finance Management, our FY'26 service fee structure has now been finalized and will go into effect as of October 1, 2025.
These fees support our continuous process improvement efforts and the implementation of additional and/or improved service features. The changes are mandated by Mass General Brigham policies, which dictate that cores recover their operating costs without generating excess revenue.
All orders that begin processing in September but complete on or after October 1, 2025, will be invoiced at current FY'25 pricing. Orders that are placed close to the end of September but are not processed before October 1, 2025, will be invoiced according to the updated FY'26 pricing structure.
We appreciate your past patronage and look forward to serving your future research needs.
Sincerely,
The CCIB DNA Core Team
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New Library Sequencing
Service
Posted on March 1, 2025
The DNA Core is pleased to offer our new Library Sequencing service. Using our Illumina NextSeq 1000 we will sequence your pre-made library with the recently released XLEAP-SBS chemistry and your choice of P1 (100M reads) or P2 (400M reads) flow cell to best meet your sequencing output needs.
Please follow this link for additional details.
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